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. 2023 Jul 1;80(7):659-660.
doi: 10.1001/jamaneurol.2023.0815.

Advocating for Demonstration of Disease Modification-Have We Been Approaching Clinical Trials in Early Alzheimer Disease Incorrectly?

Vincent Planche  1   2 , Nicolas Villain  3   4
Affiliations

Advocating for Demonstration of Disease Modification-Have We Been Approaching Clinical Trials in Early Alzheimer Disease Incorrectly?

Vincent Planche et al. JAMA Neurol. .
No abstract available

Plain language summary

This Viewpoint discusses the benefits of clinical trials with a delayed-start design and analysis of downstream biomarkers to examine whether antimyeloid immunotherapy changes the course of early Alzheimer disease.

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