Resilient brains run out of (c)GAS

Andrea Francesca M Salvador^{1

2

3}, Jonathan Kipnis^{4

5}

Affiliations

¹ Brain Immunology and Glia (BIG) Center, Washington University in St. Louis, St. Louis, MO, USA.
² Department of Pathology and Immunology, Division of Immunobiology, Washington University in St. Louis, St. Louis, MO, USA.
³ Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, USA.
⁴ Brain Immunology and Glia (BIG) Center, Washington University in St. Louis, St. Louis, MO, USA. kipnis@wustl.edu.
⁵ Department of Pathology and Immunology, Division of Immunobiology, Washington University in St. Louis, St. Louis, MO, USA. kipnis@wustl.edu.

Comment

Andrea Francesca M Salvador et al. Nat Immunol. 2023 May.

. 2023 May;24(5):741-742.

doi: 10.1038/s41590-023-01485-2.

Andrea Francesca M Salvador^{1

2

3}, Jonathan Kipnis^{4

5}

¹ Brain Immunology and Glia (BIG) Center, Washington University in St. Louis, St. Louis, MO, USA.
² Department of Pathology and Immunology, Division of Immunobiology, Washington University in St. Louis, St. Louis, MO, USA.
³ Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, USA.
⁴ Brain Immunology and Glia (BIG) Center, Washington University in St. Louis, St. Louis, MO, USA. kipnis@wustl.edu.
⁵ Department of Pathology and Immunology, Division of Immunobiology, Washington University in St. Louis, St. Louis, MO, USA. kipnis@wustl.edu.

No abstract available

Comment on

Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Udeochu JC, Amin S, Huang Y, Fan L, Torres ERS, Carling GK, Liu B, McGurran H, Coronas-Samano G, Kauwe G, Mousa GA, Wong MY, Ye P, Nagiri RK, Lo I, Holtzman J, Corona C, Yarahmady A, Gill MT, Raju RM, Mok SA, Gong S, Luo W, Zhao M, Tracy TE, Ratan RR, Tsai LH, Sinha SC, Gan L. Udeochu JC, et al. Nat Neurosci. 2023 May;26(5):737-750. doi: 10.1038/s41593-023-01315-6. Epub 2023 Apr 24. Nat Neurosci. 2023. PMID: 37095396 Free PMC article.

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