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Meta-Analysis
. 2023 Oct;20(8):3073-3080.
doi: 10.1111/iwj.14182. Epub 2023 Apr 24.

The effect of the use of postoperative antibiotic prophylaxis compared with non-use for stented distal hypospadias repair wound: A meta-analysis

Ruipeng Tang  1 , Li Wan  1 , Zhengjin Yi  1 , Yun Luo  1 , Xupan Wei  1 , Shubin Wang  1 , Chuan Xiao  1
Affiliations
Meta-Analysis

The effect of the use of postoperative antibiotic prophylaxis compared with non-use for stented distal hypospadias repair wound: A meta-analysis

Ruipeng Tang et al. Int Wound J. 2023 Oct.

Retraction in

Abstract

A meta-analysis investigation to measure the influence of the usage of postoperative antibiotic prophylaxis (POP) compared with non-usage for stented distal hypospadias repair (SDHR). A comprehensive literature inspection till February 2023 was applied and 1067 interrelated investigations were reviewed. The 10 chosen investigations enclosed 1398 individuals with SDHR in the chosen investigations starting point, 812 of them were using POP, and 586 were not using POP. Odds ratio (OR) in addition to 95% confidence intervals (CIs) were used to compute the value of the effect of the usage of POP compared with non-usage for SDHR by the dichotomous and continuous approaches and a fixed or random model. No significant difference was found between individuals using POP and not using POP in posthypospadias repair problem (PRP) (OR, 0.99; 95% CI, 0.42-2.34, P = .97) with moderate heterogeneity (I2 = 69%), posthypospadias repair infection problem (PRIP) (OR, 0.56; 95% CI, 0.30-1.06, P = .08) with no heterogeneity (I2 = 15%), and overall composite posthypospadias repair wound healing associated problem (OCPRWHAP) (OR, 1.27; 95% CI, 0.61-2.63, P = .53) with moderate heterogeneity (I2 = 59%) for SDHR. No significant difference was found between individuals using POP and not using POP in PRP, PRIP, and OCPRWHAP for SDHR. However, cautilised of the small sample sizes of several chosen investigations for this meta-analysis, care must be exercised when dealing with its values, for example, the low P-value of the PRIP.

Keywords: posthypospadias repair infection problem; posthypospadias repair problem; postoperative antibiotic prophylaxis; stented distal hypospadias repair.

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Figures

FIGURE 1
FIGURE 1
Shows a flowchart of the investigation process
FIGURE 2
FIGURE 2
The effect's forest plot of the POP in SDHR individuals on PRP
FIGURE 3
FIGURE 3
The effect's forest plot of the POP in SDHR individuals on PRIP
FIGURE 4
FIGURE 4
The effect's forest plot of the POP in SDHR individuals on OCPRWHAP
See this image and copyright information in PMC

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