Neurokinin Receptor Antagonist, Fezolinetant, for Treatment of Menopausal Vasomotor Symptoms
- PMID: 37097747
- PMCID: PMC10583986
- DOI: 10.1210/clinem/dgad209
Neurokinin Receptor Antagonist, Fezolinetant, for Treatment of Menopausal Vasomotor Symptoms
Keywords: KNDy; fezolinetant; neurokinin 3 receptor antagonist; nonhormonal; vasomotor symptoms.
Comment on
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Efficacy and Safety of Fezolinetant in Moderate to Severe Vasomotor Symptoms Associated With Menopause: A Phase 3 RCT.J Clin Endocrinol Metab. 2023 Jul 14;108(8):1981-1997. doi: 10.1210/clinem/dgad058. J Clin Endocrinol Metab. 2023. PMID: 36734148 Free PMC article. Clinical Trial.
References
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- Rance NE, Dacks PA, Mittelman-Smith MA, Romanovsky AA, Krajewski-Hall SJ. Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: a novel hypothesis on the mechanism of hot flushes. Front Neuroendocrinol. 2013;34(3):211‐227. Doi: 10.1016/j.yfrne.2013.07.003 - DOI - PMC - PubMed
