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Comment
. 2023 Apr 24;33(8):R311-R313.
doi: 10.1016/j.cub.2023.03.046.

Olfaction: Allosteric modulation

Samuel Caton  1 , Adam Dewan  2
Affiliations
Free article
Comment

Olfaction: Allosteric modulation

Samuel Caton et al. Curr Biol. .
Free article

Abstract

New research indicates that the odor-evoked responses of human olfactory receptors can be enhanced via the non-competitive binding of an allosteric modulator. This modulatory mechanism adds an additional layer of complexity to the peripheral encoding of odors.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Allosteric modulation of a human odorant receptor.
    Trimmer C, Arroyave R, Vuilleumier C, Wu L, Dumer A, DeLaura C, Kim J, Pierce GM, Borisovska M, De Nanteuil F, Emberger M, Varganov Y, Margot C, Rogers ME, Pfister P. Trimmer C, et al. Curr Biol. 2023 Apr 24;33(8):1523-1534.e4. doi: 10.1016/j.cub.2023.03.016. Epub 2023 Mar 27. Curr Biol. 2023. PMID: 36977419

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