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. 2023 Apr 21;69(4):e20221733.
doi: 10.1590/1806-9282.20221733. eCollection 2023.

Does enteral nutrition through a percutaneous endoscopic gastrostomy, attenuate Helicobacter pylori colonization?: is it worth mentioning?

Ali Muhtaroglu  1 , Ilker Sengul  1   2 , Demet Sengul  3 , Tugrul Kesicioglu  1 , Demet Seker  4 , Muhammed Aydin  5 , Ahmet Cumhur Dulger  6
Affiliations

Does enteral nutrition through a percutaneous endoscopic gastrostomy, attenuate Helicobacter pylori colonization?: is it worth mentioning?

Ali Muhtaroglu et al. Rev Assoc Med Bras (1992). .

Abstract

Objective: In patients who experience difficulties in oral feeding, alimentary intake can be supported by creating direct access into the stomach through a percutaneous endoscopic gastrostomy. The present study purposed to compare naïve and exchanged percutaneous endoscopic gastrostomy tubes in terms of Helicobacter pylori infection and other clinical characteristics.

Methods: A total of 96 cases who underwent naïve or exchanged percutaneous endoscopic gastrostomy procedures with various indications were incorporated into the study. The patients' demographic data, such as age and gender, etiology of percutaneous endoscopic gastrostomy, anti-HBs status, Helicobacter pylori status, the presence of atrophy and intestinal metaplasia, biochemical parameters, and lipid profiles, had been analyzed. In addition, the anti-HCV and anti-HIV statuses had also been evaluated.

Results: The most common indication for percutaneous endoscopic gastrostomy placement was dementia in 26 (27.08%) cases (p=0.033). The presence of Helicobacter pylori positivity was significantly lower in the exchange group compared to the naïve group (p=0.022). Total protein, albumin, and lymphocyte levels were significantly higher in the exchange group compared to the naïve group (both p=0.001), and the mean calcium, hemoglobin, and hematocrit levels were statistically significantly higher in the exchange group (p<0.001).

Conclusion: Preliminary outcomes of the present study revealed that enteral nutrition attenuates the incidence of Helicobacter pylori infection. Considering the acute-phase reactant, the significantly lower ferritin values in the exchange group suggest that there is no active inflammatory process in the patients and that immunity is sufficient.

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Conflict of interest statement

Conflicts of interest: tThe authors declare that there are no conflicts of interest.

Figures

Figure 1
Figure 1. Etiologies of the percutaneous endoscopic gastrostomy application.
See this image and copyright information in PMC

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