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. 2023 Apr:21 Suppl 2:9-12.
doi: 10.1111/ddg.15094_g.

[Ansprechen einer CARD14-assoziierten papulosquamösen Eruption auf den anti-IL17A-Antikörper Ixekizumab]

[Article in German]
Benjamin Klein  1 , Regina Treudler  1 , Konstantin Dumann  1 , Andreas Boldt  2 , Isabell Schumann  3 , Jan C Simon  1 , Manfred Kunz  1
Affiliations

[Ansprechen einer CARD14-assoziierten papulosquamösen Eruption auf den anti-IL17A-Antikörper Ixekizumab]

[Article in German]
Benjamin Klein et al. J Dtsch Dermatol Ges. 2023 Apr.
No abstract available

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References

LITERATUR

    1. Fuchs-Telem D, Sarig O, van Steensel MAM, et al. Familial pityriasis rubra pilaris is caused by mutations in CARD14. Am J Hum Genet. 2012;91(1):163-70.
    1. Craiglow BG, Boyden LM, Hu R, et al. CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris. J Am Acad Dermatol. 2018;79(3):487-94.
    1. Mellett M, Meier B, Mohanan D, et al. CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17-Mediated Psoriasiform Skin Inflammation In Vivo. J Invest Dermatol. 2018;138(9):2010-23.
    1. Wang M, Zhang S, Zheng G, et al. Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A. Immunity. 2018;49(1):66-79.e5.
    1. Haynes D, Strunck JL, Topham CA, et al. Evaluation of Ixekizumab Treatment for Patients With Pityriasis Rubra Pilaris: A Single-Arm Trial. JAMA Dermatol. 2020; 156(6): 668-75.

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