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. 2023 Sep;53(9):e14011.
doi: 10.1111/eci.14011. Epub 2023 May 5.

Endovascular aortic repair impact on myocardial contractility: A prospective study

Giovanni Spinella  1   2 , Gian Antonio Boschetti  1   2 , Matteo Bauckneht  3   4 , Stefano Raffa  3   4 , Cecilia Marini  3   5 , Alice Finotello  1   2 , Bianca Pane  1   2 , Giovanni Pratesi  1   2 , Domenico Palombo  1   2 , Gianmario Sambuceti  3   4
Affiliations

Endovascular aortic repair impact on myocardial contractility: A prospective study

Giovanni Spinella et al. Eur J Clin Invest. 2023 Sep.

Abstract

Background: This study aimed to estimate if the altered sphygmic wave transmission may affect the left ventricular (LV) contractile function in patients undergoing endovascular aortic repair (EVAR).

Methods: A prospective single-centre study was carried out on consecutive patients undergoing EVAR for abdominal aortic aneurysm. A preoperative and 6-month single photon emission computed tomography (SPECT) with arterial stiffness measurement were performed to evaluate variations in pressure wave curve and myocardial perfusion parameters.

Results: From 2018 to 2020 a total of 16 patients were included in the study. Among the parameters evaluated, we found a measurable reduction of the reflected wave transit time from pre- to postoperative period, for both stress (115.13 ± 7.2 ms-111.1 ± 7.0 ms, p = .08) and rest SPECT acquisitions (115.3 ± 6.2 ms-112.2 ± 5.6 ms, p = .1). Unidirectional increase of both LV end-systolic volume (34 ± 9 mL-39 ± 8 mL, p = .02) and end-diastolic volume (85 ± 34 mL-89 ± 29 mL, p = .6) was also observed. Lastly, the ratio between the end-systolic pressure and the end-systolic volume (maximal systolic myocardial stiffness) decreased from 3.6 ± 1.5 mmHg/mL to 2.66 ± .74 mmHg/mL (p = .03).

Conclusions: Our data showed that EVAR induced an altered transmission of the sphygmic wave associated with an early LV contractile impairment.

Keywords: abdominal aortic aneurysm; arterial stiffness; contractile function; endovascular aortic repair; left ventricular afterload; single photon emission computed tomography.

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References

REFERENCES

    1. Suckow BD, Goodney PP, Columbo JA, et al. National trends in open surgical, endovascular, and branched-fenestrated endovascular aortic aneurysm repair in Medicare patients. J Vasc Surg. 2018;67(6):1690-1697.e1.
    1. Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018;67(1):2-77.e2. doi:10.1016/j.jvs.2017.10.044
    1. Wanhainen A, Verzini F, Van Herzeele I, et al. Editor's choice - European Society for Vascular Surgery (ESVS) 2019 clinical practice guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysms. Eur J Vasc Endovasc Surg. 2019;57(1):8-93.
    1. Li B, Khan S, Salata K, et al. A systematic review and meta-analysis of the long-term outcomes of endovascular versus open repair of abdominal aortic aneurysm. J Vasc Surg. 2019;70(3):954-969.e30.
    1. Antoniou GA, Antoniou SA, Torella F. Editor's choice - endovascular vs. open repair for abdominal aortic aneurysm: systematic review and meta-analysis of updated Peri-operative and long term data of randomised controlled trials. Eur J Vasc Endovasc Surg. 2020;59(3):385-397.

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