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Case Reports
. 2023 Jul;87(1):e8-e11.
doi: 10.1016/j.jinf.2023.04.015. Epub 2023 Apr 24.

Risk of severe outcomes among SARS-CoV-2 Omicron BA.4 and BA.5 cases compared to BA.2 cases in England

Affiliations
Case Reports

Risk of severe outcomes among SARS-CoV-2 Omicron BA.4 and BA.5 cases compared to BA.2 cases in England

Nurin Abdul Aziz et al. J Infect. 2023 Jul.
No abstract available

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Conflict of interest statement

Declaration of Competing Interest GD declares that his employer’s predecessor organisation, Public Health England, received funding from GlaxoSmithKline for a research project related to influenza antiviral treatment. This preceded and had no relation to COVID-19, and GD had no role in and received no funding from the project. All other authors report no potential conflicts.

Figures

Fig. 1
Fig. 1
(A) Incidence of all confirmed COVID-19 Omicron BA.2, BA.4, and BA.5 in England between 1 April 2022 and 1 August 2022. (B) Incidence of individuals with BA.2, BA.4, and BA.5 included in the analysis by outcome status, according to outcome definition 1 where cases are individuals admitted ≥ 2 days or died within 2 days of attending ED and controls are individuals discharged from ED or admitted for< 2 days.

References

    1. Kang SW, Park H, Kim JY, Lim SY, Lee S, Bae JY, et al. Comparison of the clinical and virological characteristics of SARS-CoV-2 Omicron BA.1/BA.2 and omicron BA.5 variants: a prospective cohort study. J Infect [Internet]; 2023 Jan 16 [cited 2023 Mar 3]. Available from: 〈https://www.journalofinfection.com/article/S0163-4453(23)00020-8/fulltext〉. - PMC - PubMed
    1. Wang Q., Guo Y., Iketani S., Nair M.S., Li Z., Mohri H., et al. Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5. Nature. 2022;608(7923):603–608. - PMC - PubMed
    1. Phua J., Weng L., Ling L., Egi M., Lim C.M., Divatia J.V., et al. Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations. Lancet Respir Med. 2020;8(5):506–517. - PMC - PubMed
    1. Davies MA, Morden E, Rosseau P, Arendse J, Bam JL, Boloko L, et al. Outcomes of laboratory-confirmed SARS-CoV-2 infection during resurgence driven by Omicron lineages BA.4 and BA.5 compared with previous waves in the Western Cape Province, South Africa. medRxiv; 2022, 2022.06.28.22276983. - PMC - PubMed
    1. Wolter N., Jassat W., Walaza S., Welch R., Moultrie H., Groome M.J., et al. Clinical severity of SARS-CoV-2 Omicron BA.4 and BA.5 lineages compared to BA.1 and Delta in South Africa. Nat Commun. 2022;13(1):5860. - PMC - PubMed