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. 2023 Jan;135(Suppl 1):18-31.
doi: 10.1007/s00508-022-02123-x. Epub 2023 Apr 20.

[Other specific types of diabetes and exocrine pancreatic insufficiency (update 2023)]

[Article in German]
Susanne Kaser  1 , Sabine E Hofer  2 , Lili Kazemi-Shirazi  3 , Andreas Festa  4 , Yvonne Winhofer  5 , Harald Sourij  6 , Helmut Brath  7 , Michaela Riedl  5 , Michael Resl  8 , Martin Clodi  8   9 , Thomas Stulnig  10 , Claudia Ress  11 , Anton Luger  5
Affiliations

[Other specific types of diabetes and exocrine pancreatic insufficiency (update 2023)]

[Article in German]
Susanne Kaser et al. Wien Klin Wochenschr. 2023 Jan.

Abstract
in English, German

The heterogenous category "specific types of diabetes due to other causes" encompasses disturbances in glucose metabolism due to other endocrine disorders such as acromegaly or hypercortisolism, drug-induced diabetes (e.g. antipsychotic medications, glucocorticoids, immunosuppressive agents, highly active antiretroviral therapy (HAART), checkpoint inhibitors), genetic forms of diabetes (e.g. Maturity Onset Diabetes of the Young (MODY), neonatal diabetes, Down‑, Klinefelter- and Turner Syndrome), pancreatogenic diabetes (e.g. postoperatively, pancreatitis, pancreatic cancer, haemochromatosis, cystic fibrosis), and some rare autoimmune or infectious forms of diabetes. Diagnosis of specific diabetes types might influence therapeutic considerations. Exocrine pancreatic insufficiency is not only found in patients with pancreatogenic diabetes but is also frequently seen in type 1 and long-standing type 2 diabetes.

Die unter der Kategorie „andere spezifische Diabetesformen“ zusammengefassten Störungen des Glukosestoffwechsels stellen pathophysiologisch und therapeutisch eine sehr heterogene Krankheitsgruppe dar. Umfasst werden Diabetesformen, die im Rahmen von anderen endokrinologischen Erkrankungen auftreten (z. B. Akromegalie, Cushing-Syndrom), medikamentös induzierte Diabetesformen (z. B. Antipsychotikatherapie, Glukokortikoidtherapie, HAART, Checkpoint-Inhibitoren, genetische Formen (z. B. i. R. eines MODY, neonataler Diabetes, Down-Syndrom, Klinefelter-Syndrom, Turner-Syndrom), pankreoprive Formen (z. B. postoperativ, Pankreatitis, Pankreastumoren, Hämochromatose, zystische Fibrose), Infektionen (z. B. kongenitale Rötelninfektion) und seltene autoimmune Formen (z. B. Stiffman-Syndrom). Die Diagnose der spezifischen Diabetesform kann die therapeutischen Erwägungen beeinflussen. Nicht nur pankreoprive Formen, sondern auch Typ 1 oder langjähriger Typ 2 Diabetes mellitus sind häufig mit einer exokrinen Pankreasinsuffizienz assoziiert.

Keywords: Diabetes due to other endocrine disorders; Drug induced diabetes; Exocrine pancreatic insufficiency; Genetic diabetes forms; Other specific diabetes types.

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References

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