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. 1986;224(3):230-3.
doi: 10.1007/BF02143060.

Pharmacological therapy for proliferative vitreoretinopathy

N D Radtke, A D Weinsieder, R J Ballou

Pharmacological therapy for proliferative vitreoretinopathy

N D Radtke et al. Graefes Arch Clin Exp Ophthalmol. 1986.

Abstract

We developed an animal model in the rabbit eye with intravitreally injected heterotransplanted bovine retinal pigment epithelial cells to test a pharmacological agent which would reduce extracellular matrix formation. Results with 20 and 60 micrograms of cis-hydroxyproline showed a 48% decrease in the rate of traction retinal detachments.

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