Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Jun;8(3):101215.
doi: 10.1016/j.esmoop.2023.101215. Epub 2023 Apr 3.

Vaccination for seasonal influenza, pneumococcal infection and SARS-CoV-2 in patients with solid tumors: recommendations of the Associazione Italiana di Oncologia Medica (AIOM)

Affiliations
Review

Vaccination for seasonal influenza, pneumococcal infection and SARS-CoV-2 in patients with solid tumors: recommendations of the Associazione Italiana di Oncologia Medica (AIOM)

P Pedrazzoli et al. ESMO Open. 2023 Jun.

Abstract

Patients with cancer have a well-known and higher risk of vaccine-preventable diseases (VPDs). VPDs may cause severe complications in this setting due to immune system impairment, malnutrition and oncological treatments. Despite this evidence, vaccination rates are inadequate. The Italian Association of Medical Oncology [Associazione Italiana di Oncologia Medica (AIOM)] has been involved in vaccination awareness since 2014. Based on a careful review of the available data about the immunogenicity, effectiveness and safety of flu, pneumococcal and anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines, we report the recommendations of the AIOM about these vaccinations in adult patients with solid tumors. The AIOM recommends comprehensive education on the issue of VPDs. We believe that a multidisciplinary care model may improve the vaccination coverage in immunocompromised patients. Continued surveillance, implementation of preventive practices and future well-designed immunological prospective studies are essential for better management of our patients with cancer.

Keywords: COVID-19; cancer; influenza; pneumonitis; vaccine hesitancy; vaccine-preventable diseases (VPDs).

PubMed Disclaimer

Conflict of interest statement

Disclosure The authors have declared no conflicts of interest.

References

    1. Doherty M., Schmidt-Ott R., Santos J.I., et al. Vaccination of special populations: protecting the vulnerable. Vaccine. 2016;34:6681–6690. - PubMed
    1. Zaorsky N.G., Churilla T.M., Egleston B.L., et al. Causes of death among cancer patients. Ann Oncol. 2017;28:400–407. - PMC - PubMed
    1. Kolobova I., Nyaku M.K., Karakusevic A., Bridge D., Fotheringham I., O’Brien M. Burden of vaccine-preventable diseases among at-risk adult populations in the US. Hum Vaccin Immunother. 2022;18(5) - PMC - PubMed
    1. Ministero della Salute Dati Coperture Vaccinali. https://www.salute.gov.it/portale/influenza/dettaglioContenutiInfluenza.... Available at.
    1. Jacobson R.M., St Sauver J.L., Rutten L.J.F. Vaccine Hesitancy. Mayo Clin Proc. 2015;90:1562–1568. - PubMed

Substances