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Review
. 2023 May;120(5):478-483.
doi: 10.1007/s00347-023-01863-z. Epub 2023 Apr 27.

[Differential diagnoses of ocular mucous membrane pemphigoid]

[Article in German]
Affiliations
Review

[Differential diagnoses of ocular mucous membrane pemphigoid]

[Article in German]
Philipp Steven. Ophthalmologie. 2023 May.

Abstract

Overall, conjunctival scarring is rare and often overlooked during routine examination. However, the differential diagnostic distinction of cicatricial mucous membrane pemphigoid from other causes is crucial for further treatment planning. Other entities that lead to conjunctival scarring, are ocular rosacea, ocular graft-versus-host disease, atopic keratoconjunctivitis, infections, trauma and further sometimes very rare diseases. Most of these differential diagnoses have in common that conjunctival scarring does not progress indefinitely if untreated, in contrast to mucous membrane pemphigoid.

Vernarbungen der Bindehaut sind insgesamt selten und werden oft übersehen. Die differenzialdiagnostische Abgrenzung des vernarbenden Schleimhautpemphigoids von anderen Ursachen ist wichtig für die weitere Therapieplanung. Zu anderen Erkrankungen, die zu einer konjunktivalen Vernarbung führen, gehören die okuläre Rosazea, die okuläre Graft-versus-Host Erkrankung, die atopische Keratokonjunktivitis, Infektionen, Traumata und weitere zum Teil sehr seltene Entitäten. Den meisten dieser Differenzialdiagnosen ist gemein, dass die Vernarbung im Gegensatz zum Schleimhautpemphigoid auch unbehandelt häufig zum Stillstand kommt.

Keywords: Conjunctiva; Graft-versus-host disease; Mucous membrane pemphigoid; Rosacea; Scarring.

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References

Literatur

    1. Ogawa Y, Kawakami Y, Tsubota K (2021) Cascade of inflammatory, fibrotic processes, and stress-induced senescence in chronic GVHD-related dry eye disease. Int J Mol Sci 22:6114 - DOI - PubMed - PMC
    1. Van Zuuren EJ, Arents BWM, van der Linden MMD, Vermeulen S, Federowics Z, Tan J (2021) Rosacea: new concepts in classification and treatment. Am J Clin Derm 22:457–465 - DOI
    1. Kitko CL, Pidala J, Schoemans HM, Lawitschka A, Flowers ME, Cowen EW, Tkaczyk E, Farhadfar N, Jain S, Steven P, Luo ZK, Ogawa Y, Stern M, Yanik GA, Cuvelier GDE, Cheng GS, Holtan SG, Schultz KR, Martin PJ, Lee SJ, Pavletic SZ, Wolff D, Paczesny S, Blazar BR, Sarantopoulos S, Socie G, Greinix H, Cutler C (2021) National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIa. The 2020 Clinical Implementation and Early Diagnosis Working Group Report. Transplant Cell Ther 27(7):545–557 - DOI - PubMed - PMC
    1. Hsu JI, Pflugfelder SC, Kim SJ (2019) Ocular complications of atopic dermatitis. Cutis 104(3):189–193 - PubMed
    1. Taylor HR, Burton MJ, Haddad D, West S, Wright H (2014) Trachoma. Lancet 384(9960):2142–2152 - DOI - PubMed

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