Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Mar 23;12(4):635.
doi: 10.3390/antibiotics12040635.

About Functional Foods: The Probiotics and Prebiotics State of Art

Affiliations
Review

About Functional Foods: The Probiotics and Prebiotics State of Art

Andrea Ballini et al. Antibiotics (Basel). .

Abstract

Poor diet, obesity and a sedentary lifestyle have a significant impact on natural microbiota disorders; specifically, the intestinal one. This in turn can lead to a multitude of organ dysfunctions. The gut microbiota contains more than 500 species of bacteria and constitutes 95% of the total number of cells in the human body, thus contributing significantly to the host's resistance to infectious diseases. Nowadays, consumers have turned to purchased foods, especially those containing probiotic bacteria or prebiotics, that constitute some of the functional food market, which is constantly expanding. Indeed, there are many products available that incorporate probiotics, such as yogurt, cheese, juices, jams, cookies, salami sausages, mayonnaise, nutritional supplements, etc. The probiotics are microorganisms that, when taken in sufficient amounts, contribute positively to the health of the host and are the focus of interest for both scientific studies and commercial companies. Thus, in the last decade, the introduction of DNA sequencing technologies with subsequent bioinformatics processing contributes to the in-depth characterization of the vast biodiversity of the gut microbiota, their composition, their connection with the physiological function-known as homeostasis-of the human organism, and their involvement in several diseases. Therefore, in this study, we highlighted the extensive investigation of current scientific research for the association of those types of functional foods containing probiotics and prebiotics in the diet and the composition of the intestinal microbiota. As a result, this study can form the foundation for a new research path based on reliable data from the literature, acting a guide in the continuous effort to monitor the rapid developments in this field.

Keywords: dysbiosis; functional foods; intestinal microbiota; microencapsulation; prebiotics; probiotics.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The gut microbiota/host axis depends on the favorable balance between the microorganisms that constitute it. Credits: Original figure by I.A. Charitos.
Figure 2
Figure 2
The human’s health benefits by probiotics strains. Credits: Original figure by I.A. Charitos.

References

    1. Kasote D., Tiozon R.N., Jr., Sartagoda K.J.D., Itagi H., Roy P., Kohli A., Regina A., Sreenivasulu N. Food Processing Technologies to Develop Functional Foods with Enriched Bioactive Phenolic Compounds in Cereals. Front. Plant Sci. 2021;12:771276. doi: 10.3389/fpls.2021.771276. - DOI - PMC - PubMed
    1. Topolska K., Florkiewicz A., Filipiak-Florkiewicz A. Functional Food-Consumer Motivations and Expectations. Int. J. Environ. Res. Public Health. 2021;18:5327. doi: 10.3390/ijerph18105327. - DOI - PMC - PubMed
    1. Arai S. Studies on functional foods in Japan—State of the art. Biosci. Biotechnol. Biochem. 1996;60:9–15. doi: 10.1271/bbb.60.9. - DOI - PubMed
    1. Baker M.T., Lu P., Parrella J.A., Leggette H.R. Investigating the Effect of Consumers’ Knowledge on Their Acceptance of Functional Foods: A Systematic Review and Meta-Analysis. Foods. 2022;11:1135. doi: 10.3390/foods11081135. - DOI - PMC - PubMed
    1. Regulation (EC) No 1924/2006 of the European Parliament and of the Council of 20 December 2006 on Nutrition and Health Claims Made on Foods. [(accessed on 8 January 2023)]. Available online: https://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2006:404:000....