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Review
. 2023 Mar 29;12(4):830.
doi: 10.3390/antiox12040830.

Understanding the Role of Chemerin in the Pathophysiology of Pre-Eclampsia

Katarzyna Pankiewicz  1 , Tadeusz Issat  1
Affiliations
Review

Understanding the Role of Chemerin in the Pathophysiology of Pre-Eclampsia

Katarzyna Pankiewicz et al. Antioxidants (Basel). .

Abstract

Chemerin is a multifaceted adipokine that is involved in multiple biological processes, including inflammation, angiogenesis, adipogenesis, and energy metabolism, as well as oxidative stress. There is a vast body of evidence for a crucial role of chemerin in the development of different cardiovascular diseases. Blood chemerin levels, as well as its placental expression, are elevated in patients with pre-eclampsia (PE) and correlate positively with the severity of the disease. This narrative review summarizes the current knowledge about the potential role of chemerin during PE development, with a particular focus on its involvement in oxidative stress and endothelial dysfunction.

Keywords: chemerin; endothelial dysfunction; oxidative stress; pre-eclampsia.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The potential role of chemerin in the pathophysiology of PE.
See this image and copyright information in PMC

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