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Editorial
. 2023 Apr 11;14(4):893.
doi: 10.3390/genes14040893.

Special Issue "DNA Replication/Repair, and the DNA Damage Response in Human Disease"

Dong Zhang  1   2 , Kristin A Eckert  3 , Marietta Y W T Lee  4
Affiliations
Editorial

Special Issue "DNA Replication/Repair, and the DNA Damage Response in Human Disease"

Dong Zhang et al. Genes (Basel). .

Abstract

Mutations of numerous genes involved in DNA replication, DNA repair, and DNA damage response (DDR) pathways lead to a variety of human diseases, including aging and cancer [...].

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Conflict of interest statement

All the authors declare no conflict of interest.

References

    1. Jackson S.P., Bartek J. The DNA-damage response in human biology and disease. Nature. 2009;461:1071–1078. doi: 10.1038/nature08467. - DOI - PMC - PubMed
    1. Ragupathi A., Singh M., Perez A.M., Zhang D. Targeting the BRCA1/2 deficient cancer with PARP inhibitors: Clinical outcomes and mechanistic insights. Front. Cell Dev. Biol. 2023;11:323. doi: 10.3389/fcell.2023.1133472. - DOI - PMC - PubMed
    1. Njeri C., Pepenella S., Battapadi T., Bambara R.A., Balakrishnan L. DNA Polymerase Delta Exhibits Altered Catalytic Properties on Lysine Acetylation. Genes. 2023;14:774. doi: 10.3390/genes14040774. - DOI - PMC - PubMed
    1. Lee M., Wang X., Zhang S., Zhang Z., Lee E.Y. Regulation and Modulation of Human DNA Polymerase delta Activity and Function. Genes. 2017;8:190. doi: 10.3390/genes8070190. - DOI - PMC - PubMed
    1. Stodola J.L., Burgers P.M. Mechanism of Lagging-Strand DNA Replication in Eukaryotes. Adv. Exp. Med. Biol. 2017;1042:117–133. - PubMed

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