A Qualitative Study Exploring Motivators and Barriers to COVID-19 Vaccine Uptake among Adults in South Africa and Zimbabwe
- PMID: 37112641
- PMCID: PMC10145404
- DOI: 10.3390/vaccines11040729
A Qualitative Study Exploring Motivators and Barriers to COVID-19 Vaccine Uptake among Adults in South Africa and Zimbabwe
Abstract
While vaccines are a well-established method of controlling the spread of infectious diseases, vaccine hesitancy jeopardizes curbing the spread of COVID-19. Through the Vaccine Information Network (VIN), this study explored barriers and motivators to COVID-19 vaccine uptake. We conducted 18 focus group discussions with male and female community members, stratified by country, age group, and-for Zimbabwe only-by HIV status. Participants' median age across both countries was 40 years (interquartile range of 22-40), and most (65.9%) were female. We conceptualized the key themes within the World Health Organization's Strategic Advisory Group of Experts on Immunization (SAGE) 3C (convenience, confidence, complacency) vaccine hesitancy model. Barriers to vaccine uptake-lack of convenience, low confidence, and high complacency-included inaccessibility of vaccines and vaccination sites, vaccine safety and development concerns, and disbelief in COVID-19's existence. Motivators to vaccine uptake-convenience, confidence, and low complacency-included accessibility of vaccination sites, user-friendly registration processes, trust in governments and vaccines, fear of dying from COVID-19, and knowing someone who had died from or become infected with COVID-19. Overall, vaccine hesitancy in South Africa and Zimbabwe was influenced by inconvenience, a lack of confidence, and high complacency around COVID-19 vaccines.
Keywords: Africa; COVID-19; SARS-CoV-2; hesitancy; vaccines.
Conflict of interest statement
L.S. is a paid member of the Pfizer COVID-19 vaccine data monitoring committee and the Pfizer C467 Program-Level External Data Monitoring Committee. All other authors declare no conflict of interest.
Figures
Similar articles
-
Factors influencing influenza vaccine uptake among adults in Johannesburg, South Africa: A qualitative study.Vaccine. 2025 May 31;57:127133. doi: 10.1016/j.vaccine.2025.127133. Epub 2025 May 7. Vaccine. 2025. PMID: 40339181
-
Exploring the impact of media and information on self-reported intentions to vaccinate against COVID-19: A qualitative interview-based study.Hum Vaccin Immunother. 2022 Nov 30;18(5):2048623. doi: 10.1080/21645515.2022.2048623. Epub 2022 Apr 13. Hum Vaccin Immunother. 2022. PMID: 35417284 Free PMC article.
-
Community organization perspectives on COVID-19 vaccine hesitancy and how they increased COVID-19 vaccine confidence: a Canadian Immunization Research Network, social sciences and humanities network study.Front Public Health. 2023 Oct 2;11:1258742. doi: 10.3389/fpubh.2023.1258742. eCollection 2023. Front Public Health. 2023. PMID: 37849717 Free PMC article.
-
Parental childhood vaccine hesitancy and predicting uptake of vaccinations: a systematic review.Prim Health Care Res Dev. 2022 Nov 4;23:e68. doi: 10.1017/S1463423622000512. Prim Health Care Res Dev. 2022. PMID: 36330835 Free PMC article.
-
Ethnic/racial minorities' and migrants' access to COVID-19 vaccines: A systematic review of barriers and facilitators.J Migr Health. 2022;5:100086. doi: 10.1016/j.jmh.2022.100086. Epub 2022 Feb 18. J Migr Health. 2022. PMID: 35194589 Free PMC article. Review.
Cited by
-
Determinants of COVID-19 vaccination acceptance based on the novel Omale INDEPT FORCIS Framework and recommendations for subsequent pandemics: a qualitative study among community members in Ebonyi state, Nigeria.Int J Equity Health. 2024 Oct 28;23(1):223. doi: 10.1186/s12939-024-02284-3. Int J Equity Health. 2024. PMID: 39468612 Free PMC article.
-
A Quantitative Study on Determinants of COVID-19 Vaccine Uptake in a Mandatory Vaccination Workplace Setting in South Africa.Int J Environ Res Public Health. 2025 Jun 12;22(6):929. doi: 10.3390/ijerph22060929. Int J Environ Res Public Health. 2025. PMID: 40566355 Free PMC article.
-
Predictors of COVID-19 vaccine uptake among adults in South Africa: multimethod evidence from a population-based longitudinal study.BMJ Glob Health. 2023 Aug;8(8):e012433. doi: 10.1136/bmjgh-2023-012433. BMJ Glob Health. 2023. PMID: 37541692 Free PMC article.
-
Barriers and enhancers to COVID-19 vaccination among healthcare workers in Zimbabwe.J Public Health Afr. 2025 Feb 18;16(1):719. doi: 10.4102/jphia.v16i1.719. eCollection 2025. J Public Health Afr. 2025. PMID: 40083473 Free PMC article.
-
Equitable access to COVID-19 vaccines in Botswana: a scoping review.Front Health Serv. 2025 Jul 29;5:1609089. doi: 10.3389/frhs.2025.1609089. eCollection 2025. Front Health Serv. 2025. PMID: 40800075 Free PMC article.
References
-
- World Health Organization WHO Coronavirus (COVID-19) Dashboard. [(accessed on 16 January 2023)]. Available online: https://covid19.who.int.
-
- World Health Organization WHO Coronavirus (COVID-19) South Africa. [(accessed on 16 January 2023)]. Available online: https://covid19.who.int/region/afro/country/za.
-
- World Health Organization WHO Coronavirus (COVID-19) Zimbabwe. [(accessed on 16 January 2023)]. Available online: https://covid19.who.int/region/afro/country/zw.
Grants and funding
LinkOut - more resources
Full Text Sources
Miscellaneous