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Review
. 2021 Nov;1(11):982-990.
doi: 10.1038/s43587-021-00136-1. Epub 2021 Nov 11.

Toward the recognition and management of sarcopenia in routine clinical care

Affiliations
Review

Toward the recognition and management of sarcopenia in routine clinical care

Elsa Dent et al. Nat Aging. 2021 Nov.

Abstract

Sarcopenia, the age-associated decline in skeletal muscle mass and function, is a major cause of functional decline and mortality in older adults. Despite its importance, sarcopenia often remains unrecognized and inadequately managed in routine clinical care. A major hinderance to its clinical integration is the variation in diagnostic tools for sarcopenia. Diagnostic tools include those of the European Working Group on Sarcopenia in Older People (versions 1 and 2), those of the Asian Working Group for Sarcopenia (versions 1 and 2), and that of the Sarcopenia Definition and Outcomes Consortium. The management decision process of sarcopenia warrants an evaluation of risk factors such as a sedentary lifestyle, inadequate exercise, poor nutritional intake, smoking, depression and living circumstances. Herein, we provide an evidence-based update of the prevention and management of sarcopenia and propose practical information to facilitate the disease's adoption into routine care.

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References

    1. Beard, J. R. et al. The World Report on Ageing and Health: a policy framework for healthy ageing. Lancet 387, 2145–2154 (2016). - PubMed - DOI
    1. Woo, J. Sarcopenia. Clin. Geriatr. Med. 33, 305–314 (2017). - PubMed - DOI
    1. Scott, D. Sarcopenia in older adults. J. Clin. Med. 8, 1844 (2019).
    1. Cruz-Jentoft, A. J. & Sayer, A. A. Sarcopenia. Lancet 393, 2636–2646 (2019). - PubMed - DOI
    1. Rosenberg, I. H. Sarcopenia: origins and clinical relevance. J. Nutr. 127, 990s–991s (1997). - PubMed - DOI

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