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. 2023 May;27(5):258-265.
doi: 10.14744/AnatolJCardiol.2022.2824.

Rationale, Design, and Methodology of the MORCOR-TURK Trial: Predictors of In-hospital MORtality in CORonary Care Patients in Turkey

Fatih Kahraman  1 , İbrahim Ersoy  2 , Ahmet Seyda Yılmaz  3 , Adem Atıcı  4 , Alpin Mert Tekin  5 , Burak Açar  6 , Çağlar Kaya  7 , Faruk Kara  8 , Feyza Kurt  9 , Fulya Avcı Demir  10 , İdris Buğra Çerik  11 , İshak Yılmaz  12 , Mehmet Koray Adalı  13 , Mehtap Yeni  14 , Mustafa Beğenç Taşcanov  15 , Mustafa Yenerçağ  16 , Mürsel Şahin  17 , Ramazan Düz  18 , Sevil Gülaştı  19 , Sefa Erdi Ömür  20 , Şahin Topuz  21 , Şıho Hidayet  22 , Yücel Kaçmaz  23 , Nazif Aygül  24
Affiliations

Rationale, Design, and Methodology of the MORCOR-TURK Trial: Predictors of In-hospital MORtality in CORonary Care Patients in Turkey

Fatih Kahraman et al. Anatol J Cardiol. 2023 May.

Abstract

Background: Coronary care units are sophisticated clinics established to reduce deaths due to acute cardiovascular events. Current data on coronary care unit mortality rates and predictors of mortality in Turkey are very limited. The MORtality predictors in CORonary care units in TURKey (MORCOR-TURK) trial was designed to provide information on the mortality rates and predictors in patients followed in coronary care units in Turkey.

Methods: The MORCOR-TURK trial will be a national, observational, multicenter, and noninterventional study conducted in Turkey. The study population will include coronary care unit patients from 50 centers selected from all regions in Turkey. All consecutive patients admitted to coronary care units with cardiovascular diagnoses between 1 and 30 September 2022 will be prospectively enrolled. All data will be collected at one point in time, and the current clinical practice will be evaluated (ClinicalTrials.gov number NCT05296694). In the first step of the study, admission diagnoses, demographic characteristics, basic clinical and laboratory data, and in-hospital management will be assessed. At the end of the first step, the predictors and rates of in-hospital mortality will be documented. The second step will be in cohort design, and discharged patients will be followed up till 1 year. Predictors of short- and long-term mortality will be assessed. Moreover, a new coronary care unit mortality score will be generated with data acquired from this cohort.

Results: The short-term outcomes of the study are planned to be shared by early 2023.

Conclusion: The MORCOR-TURK trial will be the largest and most comprehensive study in Turkey evaluating the rates and predictors of in-hospital mortality of patients admitted to coronary care units.

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Figures

Figure 1.
Figure 1.
Geographic distribution of the MORCOR-TURK study centers in Turkey. MORCOR-TURK, MORtality predictors in CORonary care units in TURKey.
Figure 2.
Figure 2.
Flow diagram illustrating patients meeting entry criteria.
Figure 3.
Figure 3.
Timeline of the MORCOR-TURK study. MORCOR-TURK, MORtality predictors in CORonary care units in TURKey.
Supplementary Figure 1.
Supplementary Figure 1.
Clinical and technological change of the coronary care unit.
See this image and copyright information in PMC

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