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Comment
. 2023 Jun;23(6):654-655.
doi: 10.1016/S1473-3099(23)00274-8. Epub 2023 Apr 26.

More data needed on efficacy and safety of monovalent vaccines against SARS-CoV-2 omicron variants

Affiliations
Comment

More data needed on efficacy and safety of monovalent vaccines against SARS-CoV-2 omicron variants

Paul A Monach et al. Lancet Infect Dis. 2023 Jun.
No abstract available

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Conflict of interest statement

PM and WB-E declare funding to their institution from Gilead for participation as site co-investigators for a completed clinical trial.

Comment on

References

    1. Wang Q, Bowen A, Tam AR, et al. SARS-CoV-2 neutralising antibodies after bivalent versus monovalent booster. Lancet Infect Dis. 2023 doi: 10.1016/S1473-3099(23)00181-0. published online March 29. - DOI - PMC - PubMed
    1. Winokur P, Gayed J, Fitz-Patrick D, et al. Bivalent omicron BA.1-adapted BNT162b2 booster in adults older than 55 years. N Engl J Med. 2023;388:214–227. - PMC - PubMed
    1. Muik A, Lui BG, Bacher M, et al. Exposure to BA.4/5 S protein drives neutralization of omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice. Sci Immunol. 2022;7 - PMC - PubMed
    1. Branche AR, Rouphael NG, Diemert DJ, et al. SARS-CoV-2 variant vaccine boosters trial: preliminary analyses. medRxiv. 2022 doi: 10.1101/2022.07.12.22277336. published online July 15. (preprint). - DOI
    1. Scheaffer SM, Lee D, Whitener B, et al. Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 omicron variant in mice. Nat Med. 2023;29:247–257. - PMC - PubMed

Supplementary concepts