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Review
. 2023 Jul 5:950:175753.
doi: 10.1016/j.ejphar.2023.175753. Epub 2023 Apr 28.

New insights into the role of long non-coding RNAs in osteoporosis

Weifei Zhang  1 , Yuheng Liu  1 , Yuanrui Luo  1 , Xiang Shu  2 , Congmin Pu  2 , Bin Zhang  3 , Pin Feng  3 , Ao Xiong  4 , Qingquan Kong  5
Affiliations
Review

New insights into the role of long non-coding RNAs in osteoporosis

Weifei Zhang et al. Eur J Pharmacol. .

Abstract

Osteoporosis is a common disease in elderly individuals, and osteoporosis can easily lead to bone and hip fractures that seriously endanger the health of elderly individuals. At present, the treatment of osteoporosis is mainly anti-osteoporosis drugs, but there are side effects associated with anti-osteoporosis drugs. Therefore, it is very important to develop early diagnostic indicators and new therapeutic drugs for the prevention and treatment of osteoporosis. Long noncoding RNAs (lncRNAs), noncoding RNAs longer than 200 nucleotides, can be used as diagnostic markers for osteoporosis, and lncRNAs play an important role in the progression of osteoporosis. Many studies have shown that lncRNAs can be the target of osteoporosis. Therefore, herein, the role of lncRNAs in osteoporosis is summarized, aiming to provide some information for the prevention and treatment of osteoporosis.

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Conflict of interest statement

Declaration of competing interest The authors declare no competing interests.