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Comment
. 2023 Jun;30(6):1615-1617.
doi: 10.1038/s41418-023-01169-2. Epub 2023 Apr 29.

Activated KRAS, polyamines, iASPP and TME: a multiple liaison in pancreatic cancer

Giovanni Blandino  1
Affiliations
Comment

Activated KRAS, polyamines, iASPP and TME: a multiple liaison in pancreatic cancer

Giovanni Blandino. Cell Death Differ. 2023 Jun.
No abstract available

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Conflict of interest statement

The author declares no competing interests.

Figures

Fig. 1
Fig. 1. Reciprocal cross-talk between RAS mutations in PDAC cells and the surrounding TME.
In the left panel, the role of ODT in polyamines synthesis is resumed accordingly to the data reported by Kalaany’s group. In the right panel, the role of iASSP in KRAS G12D and KRAS G12D/mutant p53R172H is depicted accordingly to the data reported by Lu’s group.
See this image and copyright information in PMC

Comment on

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