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. 2022 Oct 31;77(5):1737-1740.
doi: 10.22092/ARI.2022.359398.2414. eCollection 2022 Oct.

Comparison of Skin Bacteria between Psoriasis Patients and Healthy Control

S Ali Abd  1 , J M J Alsaffar  1 , A K Agop  1 , E J Kadhem  2
Affiliations

Comparison of Skin Bacteria between Psoriasis Patients and Healthy Control

S Ali Abd et al. Arch Razi Inst. .

Abstract

Psoriasis is an autoimmune, persistent, inflammatory skin illness that is influenced by a variety of circumstances. Psoriasis etiology is strongly linked to bacteria, particularly those in the pharynx and skin. This research intended to deepen our understanding by elucidating the connection between the skin microbiome and psoriasis to improve therapeutic balance using probiotics, antimicrobials, and even topical microbiota transplantation. In this work, the culture-dependent approach is utilized to compare the skin microbiomes of psoriatic and healthy individuals. On brane-heart infusion agar, swabs from 60 psoriasis patients in the flare-up stag and 40 healthy controls were cultured and grown for 48 hours. The resultant colonies were then subcultured and purified to produce a single pure colony. Using Macconkey agar for preliminary colony identification, Vitek then characterized the purified colonies. The results revealed substantial bacterial species and phyla variations between psoriatic patients and healthy controls. In addition, increased rates of opportunistic infections Pseudomonas stutzeri and Staphylococcus pseudintermedius were detected in psoriatic patients' normal skin and lesions.

Keywords: Dysbiosis; Psoriasis; Skin Microbiome.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Figure 1
Figure 1
Bar chart declare the frequency % of skin bacteria species comparison between psoriatic patients' normal skin, lesional skin, and healthy skin in controls
Figure 2
Figure 2
Bar chart declares the frequency % of skin bacteria phyla comparison between psoriatic patients and healthy control
See this image and copyright information in PMC

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