Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 Apr 12:10:1174902.
doi: 10.3389/fcvm.2023.1174902. eCollection 2023.

Editorial: Lipids and inflammation in health and disease, volume II

Evgeny Bezsonov  1   2   3   4 , Mirza S Baig  5 , Michael Bukrinsky  6 , Veronika Myasoedova  7 , Alessio Ravani  7 , Vasily Sukhorukov  2 , Dongwei Zhang  8 , Victoria Khotina  1   2 , Alexander Orekhov  9
Affiliations
Editorial

Editorial: Lipids and inflammation in health and disease, volume II

Evgeny Bezsonov et al. Front Cardiovasc Med. .
No abstract available

Keywords: LDL; atherogenicity; atherosclerosis; inflammation; lipids.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Pathological factors contributing to the development of atherosclerosis. Atherogenic LDL (desialylated, oxidized, and electronegative ones) induces lipid accumulation in endothelial cells and infiltrating macrophages, leading to foam cell formation, inflammation, and further progression of atherosclerosis. There are additional factors that contribute (or potentially contribute) to the development of atherogenesis, such as low levels of HDL, sialidase, and sialyl/galactosyltransferase activities leading to the generation of atherogenic LDL, intolerance to pro-inflammatory stimulation (including stimulation by atherogenic LDL), atherosclerosis-associated non-coding RNA (ncRNA), and exosomes.
See this image and copyright information in PMC

References

    1. Malekmohammad K, Bezsonov EE, Rafieian-Kopaei M. Role of lipid accumulation and inflammation in atherosclerosis: focus on molecular and cellular mechanisms. Front Cardiovasc Med. (2021) 8:707529. 10.3389/fcvm.2021.707529 - DOI - PMC - PubMed
    1. Poznyak AV, Bezsonov EE, Popkova TV, Starodubova AV, Orekhov AN. Immunity in atherosclerosis: focusing on T and B cells. IJMS. (2021) 22:8379. 10.3390/ijms22168379 - DOI - PMC - PubMed
    1. Mezentsev A, Bezsonov E, Kashirskikh D, Baig MS, Eid AH, Orekhov A. Proatherogenic sialidases and desialylated lipoproteins: 35 years of research and current state from bench to bedside. Biomedicines. (2021) 9:600. 10.3390/biomedicines9060600 - DOI - PMC - PubMed
    1. Mushenkova NV, Bezsonov EE, Orekhova VA, Popkova TV, Starodubova AV, Orekhov AN. Recognition of oxidized lipids by macrophages and its role in atherosclerosis development. Biomedicines. (2021) 9:915. 10.3390/biomedicines9080915 - DOI - PMC - PubMed
    1. Vakhtangadze T, Singh Tak R, Singh U, Baig MS, Bezsonov E. Gender differences in atherosclerotic vascular disease: from lipids to clinical outcomes. Front Cardiovasc Med. (2021) 8:707889. 10.3389/fcvm.2021.707889 - DOI - PMC - PubMed

Publication types

LinkOut - more resources