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. 2022 Dec 26;33(2):235-239.
doi: 10.1055/s-0042-1759857. eCollection 2023 Apr.

Catastrophic Antiphospholipid Syndrome: A Case Series

Navya Christopher  1 , Gopinath Periaswamy  1 , Venkatesh Kasi Arunachalam  1 , V Mangalakumar  2 , Pankaj Mehta  1 , Mathew Cherian  1
Affiliations

Catastrophic Antiphospholipid Syndrome: A Case Series

Navya Christopher et al. Indian J Radiol Imaging. .

Abstract

Catastrophic antiphospholipid syndrome (CAPS) is the rare but most severe form of antiphospholipid syndrome with multiple organ ischemia developing over a short period of time. CAPS should be considered when imaging suggests an acute and concurrent multiorgan ischemia, associated with positive antiphospholipid antibodies. As CAPS can have fulminant irreversible complications, its early recognition is important to initiate the treatment promptly. We present three patients of CAPS who were managed at our institution.

Keywords: CAPS; antiphospholipid syndrome; catastrophic antiphospholipid syndrome.

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Conflict of interest statement

Conflict of Interest None declared.

Figures

Fig. 1
Fig. 1
Sagittal ( A ) and axial ( B-D ) sections of contrast CT thorax and abdomen of case 1 show ( A ) thrombus within the posterior basal segmental branch of left right lobe pulmonary artery (arrow), ( B ) multiple infarcts in the spleen and liver (arrows), ( C ) infarct in the left adrenal gland and ( D ) infarct in the right kidney - suggesting multifocal infarcts of various organs.
Fig. 2
Fig. 2
Contrast CT axial sections of case 2 show ( A ) infarcts in the spleen (arrow) and ( B ) infarcts in right kidney (arrow).
Fig. 3
Fig. 3
CT brain of case 2 taken 5 days later shows infarct in right parietal region (arrows).
Fig. 4
Fig. 4
Coronal and axial sections of contrast CT abdomen of case 3 show ( A ) ( B ) multiple wedge shaped infarcts in right kidney and global infarct of left kidney (arrow), ( C ) infarcts are seen in the spleen also (arrow), ( D ) thrombus (arrow) is noted in the left renal artery.
Fig. 5
Fig. 5
Axial sections of CT pulmonary angiography of case 3 show ( A ) thrombi within the right and left pulmonary arteries and segmental branches (arrows).
See this image and copyright information in PMC

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