Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 May-Jun;13(3):392-397.
doi: 10.1016/j.jobcr.2023.03.014. Epub 2023 Apr 13.

A computed tomographic evaluation of effect of mandibular advancement device at two different horizontal jaw positions in patients with obstructive sleep apnea

Affiliations

A computed tomographic evaluation of effect of mandibular advancement device at two different horizontal jaw positions in patients with obstructive sleep apnea

Pooran Chand et al. J Oral Biol Craniofac Res. 2023 May-Jun.

Erratum in

Abstract

Statement of problem: Studies pertaining to the objective assessments of the efficacy of mandibular advancement device in patients with obstructive sleep apnea are scarce.

Purpose: The purpose of this clinical study was to evaluate the effect of MAD at two different horizontal positions of mandible on upper airway dimensions through computed tomography.

Material and methods: Twenty-nine consenting participants satisfying predetermined inclusion and exclusion criteria were enrolled and an adjustable two-piece MAD was fabricated at 50% maximum mandibular protrusion and after 4 weeks was adjusted to 70% protrusion. CT scans were obtained at baseline, 4 weeks after delivering MAD with 50% mandibular protrusion, and then after 4 weeks with 70% mandibular protrusion. Cross sectional area with diameters (lateral and anteroposterior) of upper airway was measured at three specific anatomic levels (retropalatal-RP, retroglossal-RG, and epiglottal-EG). Data were analyzed using the Student t-test for parametric analysis.

Results: Intragroup comparison revealed a statistically significant increase in lateral & anteroposterior dimensions as well as cross sectional area at all three anatomical levels at 4 weeks after MAD with 50% mandibular protrusion compared with baseline and 4 weeks after MAD with 70% mandibular protrusion compared with baseline. However, the difference between lateral and anteroposterior dimensions with MAD at 70% protrusion compared with MAD at 50% protrusion was not statistically significant. The difference between cross-sectional area was found to be statistically significant.

Conclusion: Mandibular advancement device at 70% mandibular protrusion is more effective compared with the device at 50% protrusion in relieving oropharyngeal obstruction seen in OSA.

PubMed Disclaimer

Figures

Image 1
Graphical abstract
Fig. 1
Fig. 1
Pharyngeal anteroposterior dimensions at retropalatal, retroglossal and epiglottal levels measured at baseline, 4 weeks after MAD at 50% protrusion, and 4 weeks after MAD at 70% protrusion.
Fig. 2
Fig. 2
Pharyngeal lateral dimensions at retropalatal, retroglossal and epiglottal levels measured at baseline, 4 weeks after MAD at 50% protrusion, and 4 weeks after MAD at 70% protrusion.
Fig. 3
Fig. 3
Pharyngeal cross-sectional dimensions at retropalatal, retroglossal and epiglottal levels measured at baseline, 4 weeks after MAD at 50% protrusion, and 4 weeks after MAD at 70% protrusion.

References

    1. Young T., Palta M., Dempsey J., Skatrud J., Weber S., Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328:1230–1235. - PubMed
    1. Guilleminault C., Quo S.D. Sleep-disordered breathing. A view at the beginning of the new Millennium. Dent Clin. 2001;45:643–656. - PubMed
    1. Kimoff R.J., Sforza E., Champagne V., Ofiara L., Gendron D. Upper airway sensation in snoring and obstructive sleep apnea. Am J Respir Crit Care Med. 2001;164:250–255. - PubMed
    1. Guilleminault C., Li K., Chen N.H., Poyares D. Two-point palatal discrimination in patients with upper airway resistance syndrome, obstructive sleep apnea syndrome, and normal control subjects. Chest. 2002;122:866–870. - PubMed
    1. Dematteis M., Lévy P., Pépin J.L. A simple procedure for measuring pharyngeal sensitivity: a contribution to the diagnosis of sleep apnoea. Thorax. 2005;60:418–426. - PMC - PubMed