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Published Erratum
. 2023 Mar 11;15(2):293-294.
doi: 10.1007/s12551-023-01050-z. eCollection 2023 Apr.

Correction to: Structure-function relationship and physiological role of apelin and its G protein coupled receptor

Affiliations
Published Erratum

Correction to: Structure-function relationship and physiological role of apelin and its G protein coupled receptor

Subhashree Murali et al. Biophys Rev. .

Abstract

[This corrects the article DOI: 10.1007/s12551-023-01044-x.].

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Figures

Fig. 1
Fig. 1
a Representation of crystal structure of APJR-AMG3054 complex (PDB: 5VBL). The modified peptide ligand is depicted in green (sticks) and the receptor is shown in orange (cartoon). b Amino acid sequence of apelin peptide isoforms. Residues of Apelin-36, Apelin-17, Apelin-13, and Pyro-glutamate (Pyr) Apelin-13 are indicated. Grey arrows show the site of cleavage by PCSK3/furin enzyme in the larger isoforms, Apelin-36 and Apelin-17 c Comparison between Apelin-17 and AMG3054. The latter is a modified cyclic peptide (cyclised between Glu10 and Lys13, indicated by dotted lines). The modified residues of AMG3054 are coloured in pink. hARG, homoarginine; CHA, cyclohexylalanine; OIC, Octahydroindole-2-carboxylic Acid; NLE, Norleucine; 4-Cl-PHE, 4-choloro-Phenylalanine

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