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. 2023 Jun;35(6):1363-1367.
doi: 10.1007/s40520-023-02419-6. Epub 2023 May 2.

Frailty and caregiver relationship quality in older patients diagnosed with transthyretin cardiac amyloidosis

Carlo Fumagalli #  1   2 , Martina Smorti #  3 , Lucia Ponti  4   5 , Francesca Pozza  3 , Alessia Argirò  2   6 , Giacomo Credi  2 , Carlo Di Mario  7 , Raffaele Marfella  1 , Niccolò Marchionni  8 , Iacopo Olivotto  2   9 , Federico Perfetto  6   10 , Andrea Ungar #  11 , Francesco Cappelli #  6   7
Affiliations

Frailty and caregiver relationship quality in older patients diagnosed with transthyretin cardiac amyloidosis

Carlo Fumagalli et al. Aging Clin Exp Res. 2023 Jun.

Erratum in

Abstract

Aim of the study was to explore frailty and quality of the relationship with the caregiver in a cohort of older patients with transthyretin cardiac amyloidosis (ATTR-CA). Sixty-eight consecutive ATTR-CA patients were recruited and assessed for frailty, depressive symptoms, quality of the relationship in terms of social support, or conflict toward caregivers, New York Heart Association Class (NYHA), and National Amyloid Center score (NAC Score) for grading disease severity. Results showed that 10% of patients were frail. Depressive symptoms were present in 46% of patients. Regression analyses showed that both mFI and depression were associated with worse perception of social support, and that mFI and NAC score were associated with higher levels of conflict perceived in the caregivers' relationship. Overall, the mFI score was associated with worse perceived social support and caregiver relationship quality. Tertiary care heart failure clinics should actively support the patient-caregiver relationship to improve quality of life.

Keywords: ATTR-CA; Caregiver; Depression; Frailty; Quality of relationship.

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