Published Erratum
doi: 10.1038/s41587-023-01805-9.
Author Correction: Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models
Rosa Lundbye Allesøe
1
2
3
, Agnete Troen Lundgaard
1
2
, Ricardo Hernández Medina
1
, Alejandro Aguayo-Orozco
1
2
, Joachim Johansen
1
2
, Jakob Nybo Nissen
1
, Caroline Brorsson
1
2
, Gianluca Mazzoni
1
2
, Lili Niu
1
, Jorge Hernansanz Biel
1
2
, Cristina Leal Rodríguez
1
, Valentas Brasas
1
, Henry Webel
1
, Michael Eriksen Benros
3
4
, Anders Gorm Pedersen
2
, Piotr Jaroslaw Chmura
1
2
, Ulrik Plesner Jacobsen
1
2
, Andrea Mari
5
, Robert Koivula
6
, Anubha Mahajan
6
, Ana Vinuela
7
8
, Juan Fernandez Tajes
6
, Sapna Sharma
9
10
11
, Mark Haid
12
, Mun-Gwan Hong
13
, Petra B Musholt
14
, Federico De Masi
1
2
, Josef Vogt
15
, Helle Krogh Pedersen
2
15
, Valborg Gudmundsdottir
1
2
, Angus Jones
16
, Gwen Kennedy
17
, Jimmy Bell
18
, E Louise Thomas
18
, Gary Frost
19
, Henrik Thomsen
20
, Elizaveta Hansen
20
, Tue Haldor Hansen
15
, Henrik Vestergaard
15
, Mirthe Muilwijk
21
, Marieke T Blom
22
, Leen M 't Hart
21
23
24
, Francois Pattou
25
, Violeta Raverdy
25
, Soren Brage
26
, Tarja Kokkola
27
, Alison Heggie
28
, Donna McEvoy
29
, Miranda Mourby
30
, Jane Kaye
30
, Andrew Hattersley
16
, Timothy McDonald
16
, Martin Ridderstråle
31
, Mark Walker
32
, Ian Forgie
33
, Giuseppe N Giordano
34
, Imre Pavo
35
, Hartmut Ruetten
14
, Oluf Pedersen
15
, Torben Hansen
15
, Emmanouil Dermitzakis
7
, Paul W Franks
31
36
37
, Jochen M Schwenk
13
, Jerzy Adamski
38
39
40
, Mark I McCarthy
6
41
42
, Ewan Pearson
33
, Karina Banasik
1
2
, Simon Rasmussen
43
, Søren Brunak
44
45
; IMI DIRECT Consortium
Collaborators,
Affiliations
Collaborators
-
IMI DIRECT Consortium:
Philippe Froguel, Cecilia Engel Thomas, Ragna Haussler, Joline Beulens, Femke Rutters, Giel Nijpels, Sabine van Oort, Lenka Groeneveld, Petra Elders, Toni Giorgino, Marianne Rodriquez, Rachel Nice, Mandy Perry, Susanna Bianzano, Ulrike Graefe-Mody, Anita Hennige, Rolf Grempler, Patrick Baum, Hans-Henrik Stærfeldt, Nisha Shah, Harriet Teare, Beate Ehrhardt, Joachim Tillner, Christiane Dings, Thorsten Lehr, Nina Scherer, Iryna Sihinevich, Louise Cabrelli, Heather Loftus, Roberto Bizzotto, Andrea Tura, Koen Dekkers, Nienke van Leeuwen, Leif Groop, Roderick Slieker, Anna Ramisch, Christopher Jennison, Ian McVittie, Francesca Frau, Birgit Steckel-Hamann, Kofi Adragni, Melissa Thomas, Naeimeh Atabaki Pasdar, Hugo Fitipaldi, Azra Kurbasic, Pascal Mutie, Hugo Pomares-Millan, Amelie Bonnefond, Mickael Canouil, Robert Caiazzo, Helene Verkindt, Reinhard Holl, Teemu Kuulasmaa, Harshal Deshmukh, Henna Cederberg, Markku Laakso, Jagadish Vangipurapu, Matilda Dale, Barbara Thorand, Claudia Nicolay, Andreas Fritsche, Anita Hill, Michelle Hudson, Claire Thorne, Kristine Allin, Manimozhiyan Arumugam, Anna Jonsson, Line Engelbrechtsen, Annemette Forman, Avirup Dutta, Nadja Sondertoft, Yong Fan, Stephen Gough, Neil Robertson, Nicky McRobert, Agata Wesolowska-Andersen, Andrew Brown, David Davtian, Adem Dawed, Louise Donnelly, Colin Palmer, Margaret White, Jorge Ferrer, Brandon Whitcher, Anna Artati, Cornelia Prehn, Jonathan Adam, Harald Grallert, Ramneek Gupta, Peter Wad Sackett, Birgitte Nilsson, Konstantinos Tsirigos, Rebeca Eriksen, Bernd Jablonka, Mathias Uhlen, Johann Gassenhuber, Tania Baltauss, Nathalie de Preville, Maria Klintenberg, Moustafa Abdalla
Affiliations
- 1 Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 2 Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
- 3 Copenhagen Research Centre for Mental Health, Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark.
- 4 Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 5 C.N.R. Institute of Neuroscience, Padova, Italy.
- 6 Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
- 7 Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
- 8 Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.
- 9 Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany.
- 10 Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany.
- 11 Chair of Food Chemistry and Molecular and Sensory Science, Technical University of Munich, Freising, Germany.
- 12 Metabolomics and Proteomics Core, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany.
- 13 Affinity Proteomics, Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Solna, Sweden.
- 14 Research and Development Global Development, Translational Medicine and Clinical Pharmacology, Sanofi-Aventis Deutschland, Frankfurt, Germany.
- 15 Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 16 University of Exeter Medical School, Exeter, UK.
- 17 The Immunoassay Biomarker Core Laboratory, School of Medicine, University of Dundee, Dundee, UK.
- 18 Research Centre for Optimal Health, Department of Life Sciences, University of Westminster, London, UK.
- 19 Section for Nutrition Research, Faculty of Medicine, Imperial College London, London, UK.
- 20 Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark.
- 21 Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
- 22 Department of General Practice, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
- 23 Department of Biomedical Data Science, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
- 24 Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
- 25 Inserm, Univ Lille, CHU Lille, Lille Pasteur Institute, EGID, Lille, France.
- 26 MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
- 27 Department of Medicine, University of Eastern Finland, Kuopio, Finland.
- 28 Institute of Cellular Medicine, Newcastle University, Newcastle, UK.
- 29 Diabetes Research Network, Royal Victoria Infirmary, Newcastle, UK.
- 30 Centre for Health, Law and Emerging Technologies (HeLEX), Faculty of Law, University of Oxford, Oxford, UK.
- 31 Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Malmö, Sweden.
- 32 Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.
- 33 Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK.
- 34 Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, CRC, Lund University, SUS, Malmö, Sweden.
- 35 Eli Lilly Regional Operations, Vienna, Austria.
- 36 Harvard T.H. Chan School of Public Health, Boston, MA, USA.
- 37 OCDEM, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
- 38 Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
- 39 Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
- 40 Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
- 41 Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
- 42 Genentech, South San Francisco, CA, USA.
- 43 Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. simon.rasmussen@cpr.ku.dk.
- 44 Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. soren.brunak@cpr.ku.dk.
- 45 Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark. soren.brunak@cpr.ku.dk.
- PMID: 37130959
- PMCID: PMC10344774
- DOI: 10.1038/s41587-023-01805-9
Item in Clipboard
Published Erratum
Author Correction: Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models
Rosa Lundbye Allesøe et al.
Nat Biotechnol.
2023 Jul.
Display options
Format
doi: 10.1038/s41587-023-01805-9.
Authors
Rosa Lundbye Allesøe
1
2
3
, Agnete Troen Lundgaard
1
2
, Ricardo Hernández Medina
1
, Alejandro Aguayo-Orozco
1
2
, Joachim Johansen
1
2
, Jakob Nybo Nissen
1
, Caroline Brorsson
1
2
, Gianluca Mazzoni
1
2
, Lili Niu
1
, Jorge Hernansanz Biel
1
2
, Cristina Leal Rodríguez
1
, Valentas Brasas
1
, Henry Webel
1
, Michael Eriksen Benros
3
4
, Anders Gorm Pedersen
2
, Piotr Jaroslaw Chmura
1
2
, Ulrik Plesner Jacobsen
1
2
, Andrea Mari
5
, Robert Koivula
6
, Anubha Mahajan
6
, Ana Vinuela
7
8
, Juan Fernandez Tajes
6
, Sapna Sharma
9
10
11
, Mark Haid
12
, Mun-Gwan Hong
13
, Petra B Musholt
14
, Federico De Masi
1
2
, Josef Vogt
15
, Helle Krogh Pedersen
2
15
, Valborg Gudmundsdottir
1
2
, Angus Jones
16
, Gwen Kennedy
17
, Jimmy Bell
18
, E Louise Thomas
18
, Gary Frost
19
, Henrik Thomsen
20
, Elizaveta Hansen
20
, Tue Haldor Hansen
15
, Henrik Vestergaard
15
, Mirthe Muilwijk
21
, Marieke T Blom
22
, Leen M 't Hart
21
23
24
, Francois Pattou
25
, Violeta Raverdy
25
, Soren Brage
26
, Tarja Kokkola
27
, Alison Heggie
28
, Donna McEvoy
29
, Miranda Mourby
30
, Jane Kaye
30
, Andrew Hattersley
16
, Timothy McDonald
16
, Martin Ridderstråle
31
, Mark Walker
32
, Ian Forgie
33
, Giuseppe N Giordano
34
, Imre Pavo
35
, Hartmut Ruetten
14
, Oluf Pedersen
15
, Torben Hansen
15
, Emmanouil Dermitzakis
7
, Paul W Franks
31
36
37
, Jochen M Schwenk
13
, Jerzy Adamski
38
39
40
, Mark I McCarthy
6
41
42
, Ewan Pearson
33
, Karina Banasik
1
2
, Simon Rasmussen
43
, Søren Brunak
44
45
; IMI DIRECT Consortium
Collaborators
-
IMI DIRECT Consortium:
Philippe Froguel, Cecilia Engel Thomas, Ragna Haussler, Joline Beulens, Femke Rutters, Giel Nijpels, Sabine van Oort, Lenka Groeneveld, Petra Elders, Toni Giorgino, Marianne Rodriquez, Rachel Nice, Mandy Perry, Susanna Bianzano, Ulrike Graefe-Mody, Anita Hennige, Rolf Grempler, Patrick Baum, Hans-Henrik Stærfeldt, Nisha Shah, Harriet Teare, Beate Ehrhardt, Joachim Tillner, Christiane Dings, Thorsten Lehr, Nina Scherer, Iryna Sihinevich, Louise Cabrelli, Heather Loftus, Roberto Bizzotto, Andrea Tura, Koen Dekkers, Nienke van Leeuwen, Leif Groop, Roderick Slieker, Anna Ramisch, Christopher Jennison, Ian McVittie, Francesca Frau, Birgit Steckel-Hamann, Kofi Adragni, Melissa Thomas, Naeimeh Atabaki Pasdar, Hugo Fitipaldi, Azra Kurbasic, Pascal Mutie, Hugo Pomares-Millan, Amelie Bonnefond, Mickael Canouil, Robert Caiazzo, Helene Verkindt, Reinhard Holl, Teemu Kuulasmaa, Harshal Deshmukh, Henna Cederberg, Markku Laakso, Jagadish Vangipurapu, Matilda Dale, Barbara Thorand, Claudia Nicolay, Andreas Fritsche, Anita Hill, Michelle Hudson, Claire Thorne, Kristine Allin, Manimozhiyan Arumugam, Anna Jonsson, Line Engelbrechtsen, Annemette Forman, Avirup Dutta, Nadja Sondertoft, Yong Fan, Stephen Gough, Neil Robertson, Nicky McRobert, Agata Wesolowska-Andersen, Andrew Brown, David Davtian, Adem Dawed, Louise Donnelly, Colin Palmer, Margaret White, Jorge Ferrer, Brandon Whitcher, Anna Artati, Cornelia Prehn, Jonathan Adam, Harald Grallert, Ramneek Gupta, Peter Wad Sackett, Birgitte Nilsson, Konstantinos Tsirigos, Rebeca Eriksen, Bernd Jablonka, Mathias Uhlen, Johann Gassenhuber, Tania Baltauss, Nathalie de Preville, Maria Klintenberg, Moustafa Abdalla
Affiliations
- 1 Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 2 Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
- 3 Copenhagen Research Centre for Mental Health, Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark.
- 4 Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 5 C.N.R. Institute of Neuroscience, Padova, Italy.
- 6 Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
- 7 Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
- 8 Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.
- 9 Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany.
- 10 Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany.
- 11 Chair of Food Chemistry and Molecular and Sensory Science, Technical University of Munich, Freising, Germany.
- 12 Metabolomics and Proteomics Core, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany.
- 13 Affinity Proteomics, Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Solna, Sweden.
- 14 Research and Development Global Development, Translational Medicine and Clinical Pharmacology, Sanofi-Aventis Deutschland, Frankfurt, Germany.
- 15 Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 16 University of Exeter Medical School, Exeter, UK.
- 17 The Immunoassay Biomarker Core Laboratory, School of Medicine, University of Dundee, Dundee, UK.
- 18 Research Centre for Optimal Health, Department of Life Sciences, University of Westminster, London, UK.
- 19 Section for Nutrition Research, Faculty of Medicine, Imperial College London, London, UK.
- 20 Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark.
- 21 Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
- 22 Department of General Practice, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
- 23 Department of Biomedical Data Science, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
- 24 Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
- 25 Inserm, Univ Lille, CHU Lille, Lille Pasteur Institute, EGID, Lille, France.
- 26 MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
- 27 Department of Medicine, University of Eastern Finland, Kuopio, Finland.
- 28 Institute of Cellular Medicine, Newcastle University, Newcastle, UK.
- 29 Diabetes Research Network, Royal Victoria Infirmary, Newcastle, UK.
- 30 Centre for Health, Law and Emerging Technologies (HeLEX), Faculty of Law, University of Oxford, Oxford, UK.
- 31 Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Malmö, Sweden.
- 32 Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.
- 33 Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK.
- 34 Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, CRC, Lund University, SUS, Malmö, Sweden.
- 35 Eli Lilly Regional Operations, Vienna, Austria.
- 36 Harvard T.H. Chan School of Public Health, Boston, MA, USA.
- 37 OCDEM, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
- 38 Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
- 39 Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
- 40 Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
- 41 Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
- 42 Genentech, South San Francisco, CA, USA.
- 43 Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. simon.rasmussen@cpr.ku.dk.
- 44 Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. soren.brunak@cpr.ku.dk.
- 45 Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark. soren.brunak@cpr.ku.dk.
- PMID: 37130959
- PMCID: PMC10344774
- DOI: 10.1038/s41587-023-01805-9
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Erratum for
-
Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.Allesøe RL, Lundgaard AT, Hernández Medina R, Aguayo-Orozco A, Johansen J, Nissen JN, Brorsson C, Mazzoni G, Niu L, Biel JH, Leal Rodríguez C, Brasas V, Webel H, Benros ME, Pedersen AG, Chmura PJ, Jacobsen UP, Mari A, Koivula R, Mahajan A, Vinuela A, Tajes JF, Sharma S, Haid M, Hong MG, Musholt PB, De Masi F, Vogt J, Pedersen HK, Gudmundsdottir V, Jones A, Kennedy G, Bell J, Thomas EL, Frost G, Thomsen H, Hansen E, Hansen TH, Vestergaard H, Muilwijk M, Blom MT, 't Hart LM, Pattou F, Raverdy V, Brage S, Kokkola T, Heggie A, McEvoy D, Mourby M, Kaye J, Hattersley A, McDonald T, Ridderstråle M, Walker M, Forgie I, Giordano GN, Pavo I, Ruetten H, Pedersen O, Hansen T, Dermitzakis E, Franks PW, Schwenk JM, Adamski J, McCarthy MI, Pearson E, Banasik K, Rasmussen S, Brunak S; IMI DIRECT Consortium. Allesøe RL, et al. Nat Biotechnol. 2023 Mar;41(3):399-408. doi: 10.1038/s41587-022-01520-x. Epub 2023 Jan 2. Nat Biotechnol. 2023. PMID: 36593394 Free PMC article.
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