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Review
. 2023 Mar 31;38(2):e476.
doi: 10.5001/omj.2023.22. eCollection 2023 Mar.

Bacterial Ocular Infections in Iran: A Systematic Review and Meta-analysis

Milad Shahini Shams Abadi  1 , Mohammad-Hassan Arjmand  2 , Farshad Kakian  3 , Abdollah Mohammadian-Hafshejani  4 , Mehdi Banitalebi-Dehkordi  1 , Hamid Heidari  5
Affiliations
Review

Bacterial Ocular Infections in Iran: A Systematic Review and Meta-analysis

Milad Shahini Shams Abadi et al. Oman Med J. .

Abstract

Objectives: Eye infections can be caused by several microorganisms and the most common causative bacterial agents are staphylococci, streptococci, and Pseudomonas aeruginosa. This study aimed to estimate the prevalence of Staphylococcus aureus, Staphylococcus epidermidis, viridans group streptococci, and P. aeruginosa as the cause of ocular infections in Iran.

Methods: We conducted a systematic search on the studies published by Iranian authors from January 2000 to December 2020 in Web of Science, PubMed, Scopus, and Embase. Eligible studies were selected according to the defined inclusion/exclusion criteria. Statistical heterogeneity between and within groups was estimated by the Q-statistic and I2 index. The funnel plots, Duval and Tweedie trim, and fill methods were obtained to evaluate the evidence of publication bias.

Results: Twenty-seven studies were included in this review. According to the meta-analysis results, the prevalence of S.epidermidis was 19.1% (95% CI: 12.5-28.1). It was estimated 6.9% (95% CI: 4.4-10.6), 6.7% (95% CI: 4.6-9.6), and 3.3% (95% CI: 1.8-5.8) for P.aeruginosa, S. aureus, and viridans streptococci, respectively.

Conclusions: S. epidermidis is the prevalent bacterial agents responsible for eye-associated infections in Iran.

Keywords: Eye Infections; Iran; Staphylococcus aureus; Staphylococcus epidermidis; Systematic Review; Viridans Streptococci, Pseudomonas aeruginosa.

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Figures

Figure 1
Figure 1
Summary of the literature search and study selection.
Figure 2
Figure 2
Forest plot of prevalence of ocular infections causative S. aureus isolates in Iran.
Figure 3
Figure 3
Forest plot of prevalence of ocular infections causative S. epidermidis isolates in Iran.
Figure 4
Figure 4
Forest plot of prevalence of ocular infections causative viridans streptococci in Iran.
Figure 5
Figure 5
Forest plot of prevalence of ocular infections causative P. aeruginosa isolates in Iran.
None
Supplementary 1: Symmetric funnel plot showing no evedince of publication bias.
See this image and copyright information in PMC

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