The global, regional, and national burden of inflammatory bowel diseases, 1990-2019: A systematic analysis for the global burden of disease study 2019

Jihye Park¹, Gwang Hun Jeong², Minjin Song³, Dong Keon Yon⁴, Seung Won Lee⁵, Ai Koyanagi⁶, Louis Jacob⁷, Karel Kostev⁸, Elena Dragioti⁹, Joaquim Radua¹⁰, Jae Hee Cheon¹¹, Jae Il Shin¹², Lee Smith¹³

Affiliations

¹ Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Republic of Korea.
² College of Medicine, Gyeongsang National University, Jinju, Republic of Korea.
³ Yonsei University College of Medicine, Seoul, Republic of Korea.
⁴ Department of Pediatrics, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Republic of Korea.
⁵ Department of Precision Medicine, Sungkyunkwan University School of medicine, Suwon, Republic of Korea.
⁶ Parc Sanitari Sant Joan de Déu/CIBERSAM, Universitat de Barcelona, Fundació Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain; ICREA, Pg. Lluis Companys 23, Barcelona, Spain.
⁷ Parc Sanitari Sant Joan de Déu/CIBERSAM, Universitat de Barcelona, Fundació Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain; Faculty of Medicine, University of Versailles Saint-Quentin-en-Yvelines, 78180 Montigny-le-Bretonneux, France.
⁸ University Hospital of Marburg, Marburg, Germany.
⁹ Pain and Rehabilitation Centre, and Department of Health, Medicine and Caring Sciences, Linkoping University, SE-581 85 Linkoping, Sweden.
¹⁰ Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology, King's College London, London, UK; Imaging of Mood- and Anxiety-Related Disorders (IMARD) Group, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Spain; Department of Clinical Neuroscience, Centre for Psychiatric Research and Education, Karolinska Institutet, Stockholm, Sweden.
¹¹ Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: geniushee@yuhs.ac.
¹² Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: shinji@yuhs.ac.
¹³ Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, CB1 1PT Cambridge, UK.

PMID: 37137806
DOI: 10.1016/j.dld.2023.04.003

The global, regional, and national burden of inflammatory bowel diseases, 1990-2019: A systematic analysis for the global burden of disease study 2019

Jihye Park et al. Dig Liver Dis. 2023 Oct.

. 2023 Oct;55(10):1352-1359.

doi: 10.1016/j.dld.2023.04.003. Epub 2023 May 2.

Authors

Affiliations

¹ Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Republic of Korea.
² College of Medicine, Gyeongsang National University, Jinju, Republic of Korea.
³ Yonsei University College of Medicine, Seoul, Republic of Korea.
⁴ Department of Pediatrics, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Republic of Korea.
⁵ Department of Precision Medicine, Sungkyunkwan University School of medicine, Suwon, Republic of Korea.
⁶ Parc Sanitari Sant Joan de Déu/CIBERSAM, Universitat de Barcelona, Fundació Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain; ICREA, Pg. Lluis Companys 23, Barcelona, Spain.
⁷ Parc Sanitari Sant Joan de Déu/CIBERSAM, Universitat de Barcelona, Fundació Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain; Faculty of Medicine, University of Versailles Saint-Quentin-en-Yvelines, 78180 Montigny-le-Bretonneux, France.
⁸ University Hospital of Marburg, Marburg, Germany.
⁹ Pain and Rehabilitation Centre, and Department of Health, Medicine and Caring Sciences, Linkoping University, SE-581 85 Linkoping, Sweden.
¹⁰ Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology, King's College London, London, UK; Imaging of Mood- and Anxiety-Related Disorders (IMARD) Group, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Spain; Department of Clinical Neuroscience, Centre for Psychiatric Research and Education, Karolinska Institutet, Stockholm, Sweden.
¹¹ Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: geniushee@yuhs.ac.
¹² Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: shinji@yuhs.ac.
¹³ Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, CB1 1PT Cambridge, UK.

PMID: 37137806
DOI: 10.1016/j.dld.2023.04.003

Abstract

Background: In recent years, the global epidemiology of inflammatory bowel disease (IBD) has changed rapidly.

Aims: We described the updated global IBD epidemiology results based on the 2019 Global Burden of Diseases, Injuries, and Risk Factors Study (GBD).

Methods: We estimated the prevalence rate, death rate, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) from GBD 2019 in 195 countries and territories between 1990 and 2019.

Results: The crude prevalence of IBD increased by 47% in 2019 globally. Accordingly, the age-standardized prevalence rate showed 19% decrease. The age-standardized death rates, YLDs, YLLs, and DALYs of IBD in 2019 decreased compared to those in 1990. The annual percentage change in age-standardized prevalence rate decreased most in United States and increased in East Asia and high-income Asia Pacific from 1990 to 2019. Continents with high socioeconomic index (SDI) had higher age-standardized prevalence rates compared to continents with low SDI. The 2019 age-standardized prevalence rate of high latitudes was higher than that of low latitudes in Asia, Europe, and North America.

Conclusion: The observed trends and geographic variations in IBD documented in the 2019 GBD study will aid policymakers in policy, research, and investment development.

Keywords: Epidemiology; Global disease burden 2019; Inflammatory bowel disease.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest None.

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- ClinicalKey
- Elsevier Science
Medical
- MedlinePlus Health Information

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

The global, regional, and national burden of inflammatory bowel diseases, 1990-2019: A systematic analysis for the global burden of disease study 2019

Affiliations

The global, regional, and national burden of inflammatory bowel diseases, 1990-2019: A systematic analysis for the global burden of disease study 2019

Authors

Affiliations

Abstract

Conflict of interest statement

MeSH terms

LinkOut - more resources

Full Text Sources

Medical