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. 2023 Mar 13:4:1-10.
doi: 10.1109/OJEMB.2023.3256181. eCollection 2023.

Localized Multi-Site Knee Bioimpedance as a Predictor for Knee Osteoarthritis Associated Pain Within Older Adults During Free-Living

Shelby Critcher  1 , Patricia Parmelee  2 , Todd J Freeborn  1
Affiliations

Localized Multi-Site Knee Bioimpedance as a Predictor for Knee Osteoarthritis Associated Pain Within Older Adults During Free-Living

Shelby Critcher et al. IEEE Open J Eng Med Biol. .

Abstract

The drastic increase in the aging population has increased the prevalence of osteoarthritis in the United States. The ability to monitor symptoms of osteoarthritis (such as pain) within a free-living environment could improve understanding of each person's experiences with this disease and provide opportunities to personalize treatments specific to each person and their experience. In this work, localized knee tissue bioimpedance and self-reports of knee pain were collected from older adults ([Formula: see text]) with and without knee osteoarthritis over 7 days of free-living to evaluate if knee tissue bioimpedance is associated with persons' knee pain experience. Within the group of persons' with knee osteoarthritis increases in 128 kHz per-length resistance and decreases in 40 kHz per-length reactance were associated with increased probability of persons having active knee pain ([Formula: see text] and [Formula: see text]).

Keywords: Bioimpendance; Knee Osteoarthritis; Older-Adults; Pain; Wearables.

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Figures

Fig. 1.
Fig. 1.
(a) Sample of OA-associated knee joint changes, (b) electrode locations to capture bioimpedance data of knee joint, and (c) wearable electronic sensing system for study data collection.
Fig. 2.
Fig. 2.
Participant 9 longitudinal resistance for days 1 and 2 of the study, including both artifact-free and artifact classified data.
Fig. 3.
Fig. 3.
Transverse 128 kHz and 8 kHz scaled resistance data plotted to illustrate correlation.
Fig. 4.
Fig. 4.
(a) Moderating effects of group in the association of knee pain with transverse per-length resistance at 128 kHz (b) Moderating effects of group in the association of knee pain with transverse per-length reactance at 40 kHz.
Fig. 5.
Fig. 5.
(a) Conditional probability for the transverse PLR (128 kHz) and (b) PLX (40 kHz) metrics as predictors for OA knee pain.
Fig. 6.
Fig. 6.
Probability of active OA pain for participant 15 d 1 and 2 data.
See this image and copyright information in PMC

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