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. 2023 Mar;16(1):56-58.
doi: 10.1177/1753495X211049987. Epub 2021 Nov 29.

Acquired haemophilia A diagnosed during pregnancy

Ayesha Ejaz  1 , Claire O'Doherty  1 , Faye A Sharpley  1 , Nicola Curry  1   2 , Susan Shapiro  1   2 , Michael J R Desborough  2   3
Affiliations

Acquired haemophilia A diagnosed during pregnancy

Ayesha Ejaz et al. Obstet Med. 2023 Mar.

Abstract

Pregnancy-associated haemophilia A is an uncommon, acquired bleeding disorder which usually presents post-partum; very rarely it may present during pregnancy. No consensus guidelines exist on the management of this condition in pregnancy and very few cases have been reported in the literature. Here we describe the case of a woman presenting with acquired haemophilia A during pregnancy and outline the management of her bleeding disorder. We contrast her case with that of two other women, presenting to the same tertiary referral centre, with acquired haemophilia A presenting post-partum. These cases highlight the heterogeneous management of this condition and how it may be successfully managed in pregnancy.

Keywords: bleeding; postpartum hemorrhage; pregnancy.

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Conflict of interest statement

The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: MD has received speaker fees and/or consultancy from Takeda, Portola and Pfizer. SS has received meeting sponsorship, speaker fees and/or consultancy from Bayer, Pfizer, NovoNordisk, Sobi. Chugai/Roche and Shire/Takeda. NC has received two CSL Behring investigator led grants, educational advisory board fees from LFB and Bayer; conference support from Bayer, NovoNordisk, CSL Behring, and Sobi; speaker fees from Sobi. The other authors have no disclosures to declare.

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