Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 May 4;18(5):e0285445.
doi: 10.1371/journal.pone.0285445. eCollection 2023.

Comparison of complications between reverse-tapered and nontapered peripherally inserted central catheters

Affiliations

Comparison of complications between reverse-tapered and nontapered peripherally inserted central catheters

Hyun Soo Bae et al. PLoS One. .

Abstract

Purpose of this study was to compare the complication rates between reverse-tapered and nontapered peripherally inserted central catheters (PICCs). In total, 407 patients who had an inpatient clinic-based PICC insertion between September 2019 and November 2019 were retrospectively analyzed. Seven PICC types were used (4 reverse tapered: 4-Fr single-lumen (n = 75), 5-Fr single-lumen (n = 78), 5-Fr double-lumen (n = 62), and 6-Fr triple-lumen (n = 61); 3 nontapered: 4-Fr single-lumen (n = 73), 5-Fr double-lumen (n = 30), and 6-Fr triple-lumen (n = 23)). Complications such as periprocedural bleeding, delayed bleeding, inadvertent removal, catheter obstruction by thrombosis, infection, and leakage were investigated. The overall complication rate was 27.1%. The complication rate was significantly higher for nontapered PICCs than reverse-tapered PICCs (50.0% vs 16.7%, P < 0.001). The overall periprocedural bleeding rate was significantly higher for nontapered PICCs than for reverse-tapered PICCs (27.0% vs 6.2%, P <0.001). The overall inadvertent removal rate was significantly higher for nontapered PICCs than for reverse-tapered PICCs (15.1% vs 3.3%, P < 0.001). There were no other significant differences in complication rates. Nontapered PICCs were associated with higher rates of periprocedural bleeding and inadvertent removal than reverse-tapered PICCs.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Inclusion and exclusion criteria.
Fig 2
Fig 2. Illustration of nontapered and reverse-tapered PICCs.
The diameters of nontapered PICC remain equal throughout the catheter. For a reversed-tapered PICC, the diameter of the catheter gradually increases over a distance of 7 cm or 2 to 3 cm from the hub.

References

    1. Amerasekera SS, Jones CM, Patel R, Cleasby MJ. Imaging of the complications of peripherally inserted central venous catheters. Clinical radiology. 2009;64(8):832–40. Epub 20090616. doi: 10.1016/j.crad.2009.02.021 . - DOI - PubMed
    1. Smith JR, Friedell ML, Cheatham ML, Martin SP, Cohen MJ, Horowitz JD. Peripherally inserted central catheters revisited. Am J Surg. 1998;176(2):208–11. doi: 10.1016/s0002-9610(98)00121-4 . - DOI - PubMed
    1. Bozaan D, Skicki D, Brancaccio A, Snyder A, Friebe S, Tupps M, et al.. Less Lumens-Less Risk: A Pilot Intervention to Increase the Use of Single-Lumen Peripherally Inserted Central Catheters. J Hosp Med. 2019;14(1):42–6. Epub 20181031. doi: 10.12788/jhm.3097 . - DOI - PubMed
    1. Chopra V, Ratz D, Kuhn L, Lopus T, Chenoweth C, Krein S. PICC-associated bloodstream infections: prevalence, patterns, and predictors. Am J Med. 2014;127(4):319–28. Epub 20140117. doi: 10.1016/j.amjmed.2014.01.001 . - DOI - PubMed
    1. Lee JH, Kim MU, Kim ET, Shim DJ, Kim IJ, Byeon JH, et al.. Prevalence and predictors of peripherally inserted central venous catheter associated bloodstream infections in cancer patients: A multicentre cohort study. Medicine (Baltimore). 2020;99(6):e19056. doi: 10.1097/MD.0000000000019056 ; PubMed Central PMCID: PMC7015558. - DOI - PMC - PubMed

Publication types

MeSH terms