ERADication of STING limits inflammation

Affiliations

¹ University of Massachusetts Chan Medical School of Medicine, Worcester, MA, USA.
² University of Massachusetts Chan Medical School of Medicine, Worcester, MA, USA. kate.fitzgerald@umassmed.edu.

Comment

Kevin MingJie Gao et al. Nat Cell Biol. 2023 May.

. 2023 May;25(5):635-636.

doi: 10.1038/s41556-023-01142-8.

¹ University of Massachusetts Chan Medical School of Medicine, Worcester, MA, USA.
² University of Massachusetts Chan Medical School of Medicine, Worcester, MA, USA. kate.fitzgerald@umassmed.edu.

No abstract available

Comment on

Endoplasmic reticulum-associated degradation shown to regulate innate immunity.
[No authors listed] [No authors listed] Nat Cell Biol. 2023 May;25(5):641-642. doi: 10.1038/s41556-023-01139-3. Nat Cell Biol. 2023. PMID: 37142790 No abstract available.
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Ji Y, Luo Y, Wu Y, Sun Y, Zhao L, Xue Z, Sun M, Wei X, He Z, Wu SA, Lin LL, Lu Y, Chang L, Chen F, Chen S, Qian W, Xu X, Chen S, Pan D, Zhou Z, Xia S, Hu CA, Liang T, Qi L. Ji Y, et al. Nat Cell Biol. 2023 May;25(5):726-739. doi: 10.1038/s41556-023-01138-4. Epub 2023 May 4. Nat Cell Biol. 2023. PMID: 37142791 Free PMC article.

1. Ji, Y. et al. Nat. Cell Biol. https://doi.org/10.1038/s41556-023-01138-4 (2023). - DOI - PubMed
1. Ablasser, A. & Chen, Z. J. Science 363, eaat8657 (2019). - DOI - PubMed
1. Gao, K. M., Marshak-Rothstein, A. & Fitzgerald, K. A. Curr. Opin. Immunol. 80, 102280 (2023). - DOI - PubMed
1. Liu, D. et al. Cell Death Differ. 26, 1735–1749 (2019). - DOI - PubMed
1. Jeltema, D., Abbott, K. & Yan, N. J. Exp. Med. 220, e20220990 (2023). - DOI - PubMed - PMC