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Review
. 2023;25(6):143-158.
doi: 10.1007/s11936-023-00982-9. Epub 2023 Apr 21.

Coronary Revascularization in Patients With Cancer

Bala Pushparaji  1 , Teodora Donisan  2 , Dinu Valentin Balanescu  3 , Jong Kun Park  4 , Dominique J Monlezun  5 , Abdelrahman Ali  5 , Ibrahim Halil Inanc  6 , Jaime Caballero  7 , Mehmet Cilingiroglu  5 , Konstantinos Marmagkiolis  5 , Cezar Iliescu  5
Affiliations
Review

Coronary Revascularization in Patients With Cancer

Bala Pushparaji et al. Curr Treat Options Cardiovasc Med. 2023.

Abstract

Purpose of review: The treatment of coronary artery disease (CAD) in cancer patients is an evolving landscape. Recent data emphasizes the importance of aggressive management of cardiovascular risk factors and diseases in improving cardiovascular health in this unique group of patients regardless of cancer type or stage.

Recent findings: Novel cancer therapeutics such as immune therapies and proteasome inhibitors have been associated with CAD. Recent stent technologies may safely allow for shorter duration (< 6 months) of dual antiplatelet therapy post-percutaneous coronary interventions. Intracoronary imaging may be useful in the decision making process in terms of stent positioning and healing.

Summary: Large registry studies have partially filled a gap left by the lack of randomized controlled trials in the treatment of CAD in cancer patients. Cardio-oncology is gaining traction as a major sub-specialty in the cardiology field given the release of the first European Society of Cardiology - Cardio-oncology guidelines in 2022.

Keywords: ACS; Acute coronary syndrome; CAD; Cancer; Cardio-oncology; Coronary artery disease; Myocardial infarction; PCI; Radiation.

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Conflict of interest statement

Conflict of InterestBala Pushparaji declares that he has no conflict of interest. Teodora Donisan declares that she has no conflict of interest. Dinu Valentin Balanescu declares that he has no conflict of interest. Jong Kun Park declares that he has no conflict of interest. Dominique J. Monlezun declares that he has no conflict of interest. Abdelrahman Ali declares that he has no conflict of interest. Ibrahim Halil Inanc declares that he has no conflict of interest. Jaime Caballero declares that he has no conflict of interest. Mehmet Cilingiroglu declares that he has no conflict of interest. Konstantinos Marmagkiolis declares that he has no conflict of interest. Cezar Iliescu declares that he has no conflict of interest.

Figures

Fig. 1
Fig. 1
Recent updates in coronary revascularization in cancer patients. ICI, immune checkpoint inhibitors; ACS, acute coronary syndrome; TTE, transthoracic echocardiogram; STEMI, ST segment elevation myocardial infarction; NSTEMI, non-ST segment elevation myocardial infarction; DAPT, dual antiplatelet therapy; FFR, fractional flow reserve; iFR, instantaneous wave-free ratio; IVUS, intravascular ultrasound; OCT, optical coherence tomography; SADIT, single-access, dual-injection technique; SHiP, Single access for Hi-risk PCI; TEG, thromboelastogram; PCI, percutaneous coronary intervention.
See this image and copyright information in PMC

References

References and Recommended Reading

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