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. 1986 Jun 11;14(11):4683-90.
doi: 10.1093/nar/14.11.4683.

A new method for predicting signal sequence cleavage sites

G von Heijne
Free PMC article

A new method for predicting signal sequence cleavage sites

G von Heijne. Nucleic Acids Res. .
Free PMC article

Abstract

A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the mature exported protein is described. The predictive accuracy is estimated to be around 75-80% for both prokaryotic and eukaryotic proteins.

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References

    1. Biochem Biophys Res Commun. 1977 Oct 10;78(3):1018-24 - PubMed
    1. Eur J Biochem. 1983 Jun 1;133(1):17-21 - PubMed
    1. J Mol Biol. 1983 Jun 25;167(2):391-409 - PubMed
    1. Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):505-19 - PubMed
    1. Eur J Biochem. 1986 Jan 2;154(1):193-6 - PubMed

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