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Comment
. 2023 May 12;8(83):eadh0597.
doi: 10.1126/sciimmunol.adh0597. Epub 2023 May 5.

See no allergen, hear no allergen, speak no allergen!

Aurore C A Gay  1   2 , Martijn C Nawijn  1   2
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See no allergen, hear no allergen, speak no allergen!

Aurore C A Gay et al. Sci Immunol. .

Abstract

Segmental allergen challenge in allergic patients with asthma reveals a previously unknown role for monocytes in the T helper 2 (TH2)-dependent inflammatory response, whereas in allergic controls without asthma, allergen unresponsiveness seems to be maintained through epithelial-myeloid cell cross-talk that prevents TH2 cell activation (see related Research Article by Alladina et al.).

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