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Editorial
. 2023 May 1;72(5):557-559.
doi: 10.2337/dbi23-0001.

"FunDNAmethyl" Mechanism for Developmental Restriction of a β-Cell Subpopulation

Cristina Aguayo-Mazzucato  1   2 , Michael L Stitzel  3   4
Affiliations
Editorial

"FunDNAmethyl" Mechanism for Developmental Restriction of a β-Cell Subpopulation

Cristina Aguayo-Mazzucato et al. Diabetes. .
No abstract available

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Conflict of interest statement

Duality of Interest. No potential conflicts of interest relevant to this article were reported.

Figures

Figure 1
Figure 1
De novo DNA methylation in PDX1+ pancreatic progenitors or NGN3+ endocrine progenitors restricts Th+ β-cells. This population becomes restricted to 1–3% of β-cells in the postnatal period but can be dynamically restored in response to high-fat diet (HFD) through demethylation. BioRender.com was used to create part of the figure. E, embryonic day.
See this image and copyright information in PMC

Comment on

References

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