hPSCs-derived Schwann cells serve for disease modeling and drug discovery
- PMID: 37146574
- DOI: 10.1016/j.stem.2023.04.013
hPSCs-derived Schwann cells serve for disease modeling and drug discovery
Abstract
In this issue, Majd et al.1 derive Schwann cells from human pluripotent stem cells (hPSCs), which can be used to study Schwann cell development and physiology and model diabetic neuropathy. hPSC-derived Schwann cells possess the molecular features of primary Schwann cells and are capable of myelination in vitro and in vivo.
Copyright © 2023 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no conflict of interests.
Comment on
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Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy.Cell Stem Cell. 2023 May 4;30(5):632-647.e10. doi: 10.1016/j.stem.2023.04.006. Cell Stem Cell. 2023. PMID: 37146583 Free PMC article.
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