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Review
. 2023 Apr;32(2):367-394.
doi: 10.1016/j.chc.2022.08.012.

Mood Disorders in Youth: Complementary and Integrative Medicine

Kirti Saxena  1 , Sherin Kurian  2 , Reena Kumar  3 , L Eugene Arnold  4 , Deborah R Simkin  5
Affiliations
Review

Mood Disorders in Youth: Complementary and Integrative Medicine

Kirti Saxena et al. Child Adolesc Psychiatr Clin N Am. 2023 Apr.

Abstract

Omega-3 polyunsaturated fatty acids, probiotics, vitamin C, vitamin D, folic acid and L-methyl folate, broad-spectrum micronutrients, N-acetylcysteine, physical activity, herbs, bright light therapy, melatonin, saffron, meditation, school-based interventions, and transcranial photobiomodulation are reviewed, with a focus on their use for treating mood disorders in children and adolescents. For each treatment, all published randomized controlled trials are summarized.

Keywords: Bipolar disorder; Children and Adolescents; Complementary and integrative medicine; Depression; Mood disorders; Omega-3 fatty acids; Vitamins.

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Conflict of interest statement

Disclosure Drs K. Saxena, S. Kurian, R. Kumar, and D.R. Simkin have no disclosures. Dr L.E. Arnold has received research funding from Supernus Pharmaceuticals, Roche/Genentech Pharmaceuticals, Otsuka Pharmaceuticals, Axial, and Young Living Essential Oils and National Institute of Health (USA, R01 MH 100144), has consulted with Pfizer Pharmaceuticals and CHADD, and been on advisory boards for Otsuka and Roche/Genentech.

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