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Case Reports
. 2023 May 5;16(5):e254195.
doi: 10.1136/bcr-2022-254195.

Atypical case of infective endocarditis

Affiliations
Case Reports

Atypical case of infective endocarditis

Abraham M Ittyachen et al. BMJ Case Rep. .

Abstract

A man in his late 40s presented to the emergency department with generalised tiredness and breathlessness. He was a known case of chronic obstructive pulmonary disease and also had a recent history of COVID-19. At arrival, he was in respiratory failure. Blood culture grew Streptococcus parasanguinis, a commensal gram-positive bacterium and a primary coloniser of the human oral cavity. Echocardiogram revealed the presence of a flail mitral valve with vegetation suggestive of infective endocarditis. Although biomarkers of inflammation/infection had improved, he continued to be in cardiac failure, and hence he underwent mitral valve replacement with a mechanical valve. This case is unique in many ways; the patient was young, had a history of COVID-19, had native valve infective endocarditis and presented with type 2 respiratory failure and not the usual 'typical' manifestations of infective endocarditis. He had refractory heart failure requiring early valve replacement. His blood culture grew S. parasanguinis, a rare cause for infective endocarditis.

Keywords: Adult intensive care; Valvar diseases.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Anteroposterior view of the chest radiograph showing cardiomegaly with perihilar infiltrates.
Figure 2
Figure 2
Echocardiogram showing vegetation (white arrow).

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References

    1. Mills MT, Al-Mohammad A, Warriner DR. Changes and advances in the field of infective endocarditis. Br J Hosp Med 2022;83:1–11. 10.12968/hmed.2021.0510 - DOI - PubMed
    1. Ritchie AI, Wedzicha JA. Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations. Clin Chest Med 2020;41:421–38. 10.1016/j.ccm.2020.06.007 - DOI - PMC - PubMed
    1. Ko FW, Chan KP, Hui DS, et al. . Acute exacerbation of COPD. Respirology 2016;21:1152–65. 10.1111/resp.12780 - DOI - PMC - PubMed
    1. Quintero-Martinez JA, Hindy J-R, Mahmood M, et al. . A clinical profile of infective endocarditis in patients with recent COVID-19: a systematic review. Am J Med Sci 2022;364:16–22. 10.1016/j.amjms.2022.02.005 - DOI - PMC - PubMed
    1. Liesenborghs L, Meyers S, Lox M, et al. . Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves. Eur Heart J 2019;40:3248–59. 10.1093/eurheartj/ehz175 - DOI - PMC - PubMed

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