Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Aug;37(8):1719-1722.
doi: 10.1038/s41375-023-01914-z. Epub 2023 May 5.

Relationship among three common hematological premalignant conditions

Affiliations

Relationship among three common hematological premalignant conditions

Nicholas J Boddicker et al. Leukemia. 2023 Aug.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Forest plot of associations between premalignant conditions of monoclonal B-cell lymphocytosis (MBL), monoclonal gammopathy of undetermined significance (MGUS), and clonal hematopoiesis (CH).
DTA CH: DNMT3A, TET2, or ASXL1 somatic mutation carrier.

References

    1. Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IBO, Berti E, et al. The 5th edition of the World Health Organization Classification of haematolymphoid tumours: lymphoid neoplasms. Leukemia. 2022;36:1720–48. doi: 10.1038/s41375-022-01620-2. - DOI - PMC - PubMed
    1. Niroula A, Sekar A, Murakami MA, Trinder M, Agrawal M, Wong WJ, et al. Distinction of lymphoid and myeloid clonal hematopoiesis. Nat Med. 2021;27:1921–7. doi: 10.1038/s41591-021-01521-4. - DOI - PMC - PubMed
    1. Slager SL, Lanasa MC, Marti GE, Achenbach SJ, Camp NJ, Abbasi F, et al. Natural history of monoclonal B-cell lymphocytosis among relatives in CLL families. Blood. 2021;137:2046–56. doi: 10.1182/blood.2020006322. - DOI - PMC - PubMed
    1. Slager SL, Parikh SA, Achenbach SJ, Norman AD, Rabe KG, Boddicker NJ, et al. Progression and survival of monoclonal B-cell lymphocytosis (MBL): a screening study of 10,139 individuals. Blood. 2022;140:1702–9. doi: 10.1182/blood.2022016279. - DOI - PMC - PubMed
    1. Kyle RA, Therneau TM, Rajkumar SV, Offord JR, Larson DR, Plevak MF, et al. A long-term study of prognosis in monoclonal gammopathy of undetermined significance. N Engl J Med. 2002;346:564–9. doi: 10.1056/NEJMoa01133202. - DOI - PubMed

Publication types