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. 1986:213:511-20.

The effects of flavonoids on human lymphocyte proliferative responses

B K Mookerjee, T P Lee, G P Logue, H A Lippes, E Middleton
  • PMID: 3714747

The effects of flavonoids on human lymphocyte proliferative responses

B K Mookerjee et al. Prog Clin Biol Res. 1986.

Abstract

Flavonoids reversibly inhibit lymphocyte proliferative responses to phytomitogens, soluble antigens and phorbol esters by blocking an early event or events that follow stimulation. Quercetin and tangeretin inhibit thymidine transport in stimulated lymphocytes. These flavonoids reversibly inhibit antigen processing by monocytes and inhibit the expression of class II histocompatibility (DR) antigens in PBM cells.

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