Detection of human chorionic gonadotropin (HCG) in fabric urine stains older than five years
- PMID: 37149739
- DOI: 10.1111/1556-4029.15274
Detection of human chorionic gonadotropin (HCG) in fabric urine stains older than five years
Abstract
Human chorionic gonadotropin (HCG) is used in clinical medicine as a particularly important indicator to determine pregnancy. In this study, it was necessary to determine whether the urine spots on car seat fabric from a murder 5 years previously were from a pregnant woman. The HCG in the dried urine spot on a car seat was detected using an immunochromatography kit. It was found that the HCG in urine can be detected for much longer periods of time than the previously reported period of approximately 6 months.
Keywords: human chorionic gonadotropin; immunochromatography; pregnancy; urine spots.
© 2023 American Academy of Forensic Sciences.
Similar articles
-
Purification of human chorionic gonadotropin from pregnancy urine by immunoaffinity chromatography using a monoclonal antibody anti-beta chain hCG.Hybridoma (Larchmt). 2005 Oct;24(5):258-62. doi: 10.1089/hyb.2005.24.258. Hybridoma (Larchmt). 2005. PMID: 16225426
-
Purification of human chorionic gonadotrophin from urine by membrane filtration affinity chromatography with a positively charged membrane.Protein Expr Purif. 1999 Jul;16(2):221-3. doi: 10.1006/prep.1999.1058. Protein Expr Purif. 1999. PMID: 10419817
-
Quantification of urinary chorionic gonadotropin in spontaneous abortion of pre-clinically recognized pregnancy: method development and analytical validation.Int J Hyg Environ Health. 2007 May;210(3-4):419-27. doi: 10.1016/j.ijheh.2007.01.022. Epub 2007 Mar 1. Int J Hyg Environ Health. 2007. PMID: 17336148
-
Immunoprocedures for detecting human chorionic gonadotropin: clinical aspects and doping control.Clin Chem. 1997 Jul;43(7):1293-8. Clin Chem. 1997. PMID: 9216477 Review.
-
Determination of human chorionic gonadotropin.Best Pract Res Clin Endocrinol Metab. 2013 Dec;27(6):783-93. doi: 10.1016/j.beem.2013.10.005. Epub 2013 Oct 26. Best Pract Res Clin Endocrinol Metab. 2013. PMID: 24275190 Review.
References
REFERENCES
-
- Hussa RO. Biosynthesis of human chorionic gonadotropin. Endocr Rev. 1980;1(3):268-94. https://doi.org/10.1210/edrv-1-3-268
-
- Pierce JG, Parsons TF. Glycoprotein hormones: structure and function. Annu Rev Biochem. 1981;50:465-95. https://doi.org/10.1146/annurev.bi.50.070181.002341
-
- Hay DL, Lopata A. Chorionic gonadotropin secretion by human embryos in vitro. J Clin Endocrinol Metab. 1988;67(6):1322-4. https://doi.org/10.1210/jcem-67-6-1322
-
- Nepomnaschy PA, Weinberg CR, Wilcox AJ, Baird DD. Urinary hCG patterns during the week following implantation. Hum Reprod. 2008;23(2):271-7. https://doi.org/10.1093/humrep/dem397
-
- Stenman UH, Tiitinen A, Alfthan H, Valmu L. The classification, functions and clinical use of different isoforms of HCG. Hum Reprod Update. 2006;12(6):769-84. https://doi.org/10.1093/humupd/dml029
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources