Detection of human chorionic gonadotropin (HCG) in fabric urine stains older than five years
- PMID: 37149739
- DOI: 10.1111/1556-4029.15274
Detection of human chorionic gonadotropin (HCG) in fabric urine stains older than five years
Abstract
Human chorionic gonadotropin (HCG) is used in clinical medicine as a particularly important indicator to determine pregnancy. In this study, it was necessary to determine whether the urine spots on car seat fabric from a murder 5 years previously were from a pregnant woman. The HCG in the dried urine spot on a car seat was detected using an immunochromatography kit. It was found that the HCG in urine can be detected for much longer periods of time than the previously reported period of approximately 6 months.
Keywords: human chorionic gonadotropin; immunochromatography; pregnancy; urine spots.
© 2023 American Academy of Forensic Sciences.
References
REFERENCES
-
- Hussa RO. Biosynthesis of human chorionic gonadotropin. Endocr Rev. 1980;1(3):268-94. https://doi.org/10.1210/edrv-1-3-268
-
- Pierce JG, Parsons TF. Glycoprotein hormones: structure and function. Annu Rev Biochem. 1981;50:465-95. https://doi.org/10.1146/annurev.bi.50.070181.002341
-
- Hay DL, Lopata A. Chorionic gonadotropin secretion by human embryos in vitro. J Clin Endocrinol Metab. 1988;67(6):1322-4. https://doi.org/10.1210/jcem-67-6-1322
-
- Nepomnaschy PA, Weinberg CR, Wilcox AJ, Baird DD. Urinary hCG patterns during the week following implantation. Hum Reprod. 2008;23(2):271-7. https://doi.org/10.1093/humrep/dem397
-
- Stenman UH, Tiitinen A, Alfthan H, Valmu L. The classification, functions and clinical use of different isoforms of HCG. Hum Reprod Update. 2006;12(6):769-84. https://doi.org/10.1093/humupd/dml029
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