Periorbital cutaneous angiomyolipoma: a case report

Abstract

Angiomyolipomas are usually found in the kidneys of patients with tuberous sclerosis. They occur less frequently in organs such as the liver, the oral cavity, the nasal cavity, the heart, the large intestines, and the lungs. Angiomyolipomas of the skin are extremely rare, and cutaneous angiomyolipomas generally occur on the elbow, the ends of digits, the ear, and the glabella. Herein we present a rare case of angiomyolipoma occurring on the face-specifically, the right upper eyelid. We propose that upper eyelid angiomyolipoma is a hamartomatous, rather than neoplastic, lesion. Although angiomyolipoma in the periocular area is rare, it should be considered in the differential diagnosis of clinically benign masses. and regular follow-up is warranted.

Keywords: Angiomyolipoma; Case reports; HMB-45; Neoplasms; Orbit; Tuberous sclerosis.

Fig. 1

A 43-year-old man with a 2×2 cm mass in his right upper eyelid.

Fig. 2

Color Doppler ultrasonography shows heteroechogenicity, awell-defined margin, and blood-filled spaces.

Fig. 3

Enhanced computed tomographic scan show a circumscribed soft tissue mass on the right upper eyelid with heterogeneous density.

Fig. 4

Intraoperative view of a well-localized mass under the orbicularis oculi muscle.

Fig. 5

A triphasic composition is seen, with mature adipose tissue, thick-walled blood vessels (circle), and a myoid component (asterisks). Hematoxylin and eosin staining (×10).

Fig. 6

Pathological findings. (A) The smooth muscle component and vascular wall are immunoreactive for smooth muscle actin (smooth muscle actin staining, ×10). (B) No positivity of human melanoma black-45 staining is shown (×10).

Fig. 7

Follow-up photograph at postoperative 6 months with no discomfort or recurrence.