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Review
. 2023 Apr 21;9(5):e15598.
doi: 10.1016/j.heliyon.2023.e15598. eCollection 2023 May.

Cholera prevention, control strategies, challenges and World Health Organization initiatives in the Eastern Mediterranean Region: A narrative review

Affiliations
Review

Cholera prevention, control strategies, challenges and World Health Organization initiatives in the Eastern Mediterranean Region: A narrative review

Evans Buliva et al. Heliyon. .

Abstract

The resurgence of cholera is presenting unusual challenges in the Eastern Mediterranean Region (EMR), where it is considered endemic in nine-member states. The risk of a cholera outbreak spreading to non-endemic countries remains high. We discuss the regional trends of cholera, regional burden, and challenges with a focus on World Health Organization (WHO) initiatives in the region that could be useful in preventing and controlling the disease in similar contexts. Despite significant progress in the control of cholera worldwide, the disease continues to be a major public health problem across the region, where it constitutes both an emerging and re-emerging threat. Recurring cholera outbreaks are an indication of deprived water and sanitation conditions as well as weak health systems, contributing to the transmission and spread of the cholera infection. We note that despite the challenges in eliminating cholera in the region, effective implementation of the proposed WHO EMR Strategic framework, among other measures, could sustain the region's cholera prevention, preparedness, and response needs.

Keywords: Cholera; Prevention and control; WHO Eastern Mediterranean Region; WHO Strategic framework.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Trend of cholera cases and deaths in Eastern Mediterranean Region, 2000–Oct 2021.
Fig. 2
Fig. 2
Cholera endemic countries in the Eastern Mediterranean region.

References

    1. Ali M., Nelson A.R., Lopez A.L., Sack D.A. Updated global burden of cholera in endemic countries. PLoS Neglected Trop. Dis. 2015;9(6) doi: 10.1371/journal.pntd.0003832. - DOI - PMC - PubMed
    1. Davis W., Narra R., Mintz E.D. Cholera. Curr. Epidem. Rep. 2018;5(3):303–315. doi: 10.1007/s40471-018-0162-z. - DOI - PMC - PubMed
    1. Clemens J.D., Nair G.B., Ahmed T., Qadri F., Holmgren J. Cholera. The Lancet. 2017;390(10101):1539–1549. doi: 10.1016/S0140-6736(17)30559-7. - DOI - PubMed
    1. GTFCC . 2017. Ending Cholera: A Global Roadmap to 2030.https://www.who.int/cholera/publications/global-roadmap.pdf
    1. Lancet Cholera: ending a 50-year pandemic. Lancet. 2017;390(10103):1623. doi: 10.1016/S0140-6736(17)32592-8. - DOI - PubMed

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