Vulnerable newborn types: Analysis of population-based registries for 165 million births in 23 countries, 2000-2021

Lorena Suárez-Idueta¹, Judith Yargawa², Hannah Blencowe², Ellen Bradley², Yemisrach B Okwaraji², Veronica Pingray³, Luz Gibbons³, Adrienne Gordon⁴, Kara Warrilow⁵, Enny S Paixao^{2

6}, Ila Rocha Falcão⁶, Sarka Lisonkova⁷, Qi Wen⁷, Francisco Mardones⁸, Raúl Caulier-Cisterna⁸, Petr Velebil⁹, Jitka Jírová¹⁰, Erzsebet Horváth-Puhó¹¹, Henrik Toft Sørensen¹¹, Luule Sakkeus¹², Lili Abuladze¹², Mika Gissler¹³, Mohammad Heidarzadeh¹⁴, Maziar Moradi-Lakeh¹⁵, Khalid A Yunis¹⁶, Ayah Al Bizri¹⁶, Shamala D Karalasingam¹⁷, Ravichandran Jeganathan¹⁸, Arturo Barranco¹⁹, Lisa Broeders²⁰, Aimée E van Dijk²⁰, Luis Huicho²¹, Hugo Guillermo Quezada-Pinedo²², Kim Nail Cajachagua-Torres²², Fawziya Alyafei²³, Mai AlQubaisi²³, Geum Joon Cho²⁴, Ho Yeon Kim²⁴, Neda Razaz²⁵, Jonas Söderling²⁵, Lucy K Smith²⁶, Jennifer Kurinczuk²⁷, Estelle Lowry²⁸, Neil Rowland²⁹, Rachael Wood^{30

31}, Kirsten Monteath³², Isabel Pereyra^{33

34}, Gabriella Pravia³⁴, Eric O Ohuma², Joy E Lawn²; National Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group

Collaborators, Affiliations

Collaborators

National Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group:
Vicki Flenady, Harriet Lawford, Gabriela Cormick, Jose Belizan, Carlos Guevel, Mauricio Lima Barreto, José Acuña, Narjes Khalili, Pascale Nakad, Nurakman Binti Baharum, Jesus Felipe Gonzalez Roldan, Sonia Lopez Alvarez, Wilmer Cristobal Guzman-Vilca, Carla Tarazona-Meza, Rodrigo M Carrillo-Larco, Tawa O Olukade, Hamdy A Ali, Bradley N Manktelow, Ruth J Matthews, Elizabeth Draper, Alan Fenton, Celina Davis, Samantha Clarke, Robert E Black, Joanne Katz, Daniel Erchick, Elizabeth Hazel, Mike Diaz, Anne C C Lee

Affiliations

¹ Mexican Society of Public Health, Mexico City, Mexico.
² Maternal, Adolescent, Reproductive & Child Health (MARCH) Centre, London School of Hygiene & Tropical Medicine, London, UK.
³ Department of Mother & Child Health, Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.
⁴ Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
⁵ Centre for Research Excellence in Stillbirth, MRI-UQ, Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia.
⁶ Centre of Data and Knowledge Integration for Health (CIDACS), Instituto Gonçalo Moniz, Fiocruz Bahia, Fundação Oswaldo Cruz, Salvador, Brazil.
⁷ Department of Obstetrics & Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada.
⁸ Pontificia Universidad Católica de Chile, Santiago, Chile.
⁹ Department of Obstetrics and Gynaecology, Institute for the Care of Mother and Child, Prague, Czech Republic.
¹⁰ Department of Data Analysis, Institute of Health Information and Statistics of the Czech Republic, Prague, Czech Republic.
¹¹ Department of Clinical Epidemiology, Aarhus University, Aarhus N, Denmark.
¹² School of Governance, Law and Society, Estonian Institute for Population Studies, Tallinn University, Tallinn, Estonia.
¹³ Department of Knowledge Brokers, THL Finnish Institute for Health and Welfare, Helsinki, Finland.
¹⁴ Department of Paediatrics, Alzahra Hospital, Tabriz, Iran.
¹⁵ Department of Community Medicine, Preventive Medicine and Public Health Research Centre, Iran University of Medical Sciences, Tehran, Iran.
¹⁶ Department of Paediatrics and Adolescent Medicine, American University of Beirut, Beirut, Lebanon.
¹⁷ Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Cyberjaya, Cyberjaya, Malaysia.
¹⁸ Department of Obstetrics & Gynaecology, Hospital Sultanah Aminah, Ministry of Health, Johor Bahru, Malaysia.
¹⁹ Directorate of Health Information, Ministry of Health, Mexico City, Mexico.
²⁰ Perined, Utrecht, The Netherlands.
²¹ Centro de Investigación en Salud Materna e Infantil, Centro de Investigación para el Desarrollo Integral y Sostenible and School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.
²² The Generation R Study Group, Department of Paediatrics, Division of Neonatology, Erasmus MC - Sophia Children's Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
²³ Hamad Medical Corporation, Doha, Qatar.
²⁴ Department of Obstetrics and Gynaecology, Korea University College of Medicine, Seoul, South Korea.
²⁵ Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
²⁶ Department of Health Sciences, College of Life Sciences, University of Leicester, Leicester, UK.
²⁷ National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
²⁸ School of Natural and Built Environment, Queen's University Belfast, Belfast, UK.
²⁹ Queen's Management School, Queen's University Belfast, Belfast, UK.
³⁰ Public Health Scotland, Edinburgh, UK.
³¹ Usher Institute, University of Edinburgh, Edinburgh, UK.
³² Department of Maternity and Sexual Health Team, Public Health Scotland, Edinburgh, UK.
³³ Catholic University of the Maule, Región del Maule, Chile.
³⁴ Department of Wellness and Health, Catholic University of Uruguay, Montevideo, Uruguay.

PMID: 37156241
DOI: 10.1111/1471-0528.17505

Vulnerable newborn types: Analysis of population-based registries for 165 million births in 23 countries, 2000-2021

Lorena Suárez-Idueta et al. BJOG. 2023.

. 2023 May 8.

doi: 10.1111/1471-0528.17505. Online ahead of print.

Authors

Collaborators

National Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group:
Vicki Flenady, Harriet Lawford, Gabriela Cormick, Jose Belizan, Carlos Guevel, Mauricio Lima Barreto, José Acuña, Narjes Khalili, Pascale Nakad, Nurakman Binti Baharum, Jesus Felipe Gonzalez Roldan, Sonia Lopez Alvarez, Wilmer Cristobal Guzman-Vilca, Carla Tarazona-Meza, Rodrigo M Carrillo-Larco, Tawa O Olukade, Hamdy A Ali, Bradley N Manktelow, Ruth J Matthews, Elizabeth Draper, Alan Fenton, Celina Davis, Samantha Clarke, Robert E Black, Joanne Katz, Daniel Erchick, Elizabeth Hazel, Mike Diaz, Anne C C Lee

Affiliations

¹ Mexican Society of Public Health, Mexico City, Mexico.
² Maternal, Adolescent, Reproductive & Child Health (MARCH) Centre, London School of Hygiene & Tropical Medicine, London, UK.
³ Department of Mother & Child Health, Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.
⁴ Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
⁵ Centre for Research Excellence in Stillbirth, MRI-UQ, Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia.
⁶ Centre of Data and Knowledge Integration for Health (CIDACS), Instituto Gonçalo Moniz, Fiocruz Bahia, Fundação Oswaldo Cruz, Salvador, Brazil.
⁷ Department of Obstetrics & Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada.
⁸ Pontificia Universidad Católica de Chile, Santiago, Chile.
⁹ Department of Obstetrics and Gynaecology, Institute for the Care of Mother and Child, Prague, Czech Republic.
¹⁰ Department of Data Analysis, Institute of Health Information and Statistics of the Czech Republic, Prague, Czech Republic.
¹¹ Department of Clinical Epidemiology, Aarhus University, Aarhus N, Denmark.
¹² School of Governance, Law and Society, Estonian Institute for Population Studies, Tallinn University, Tallinn, Estonia.
¹³ Department of Knowledge Brokers, THL Finnish Institute for Health and Welfare, Helsinki, Finland.
¹⁴ Department of Paediatrics, Alzahra Hospital, Tabriz, Iran.
¹⁵ Department of Community Medicine, Preventive Medicine and Public Health Research Centre, Iran University of Medical Sciences, Tehran, Iran.
¹⁶ Department of Paediatrics and Adolescent Medicine, American University of Beirut, Beirut, Lebanon.
¹⁷ Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Cyberjaya, Cyberjaya, Malaysia.
¹⁸ Department of Obstetrics & Gynaecology, Hospital Sultanah Aminah, Ministry of Health, Johor Bahru, Malaysia.
¹⁹ Directorate of Health Information, Ministry of Health, Mexico City, Mexico.
²⁰ Perined, Utrecht, The Netherlands.
²¹ Centro de Investigación en Salud Materna e Infantil, Centro de Investigación para el Desarrollo Integral y Sostenible and School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.
²² The Generation R Study Group, Department of Paediatrics, Division of Neonatology, Erasmus MC - Sophia Children's Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
²³ Hamad Medical Corporation, Doha, Qatar.
²⁴ Department of Obstetrics and Gynaecology, Korea University College of Medicine, Seoul, South Korea.
²⁵ Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
²⁶ Department of Health Sciences, College of Life Sciences, University of Leicester, Leicester, UK.
²⁷ National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
²⁸ School of Natural and Built Environment, Queen's University Belfast, Belfast, UK.
²⁹ Queen's Management School, Queen's University Belfast, Belfast, UK.
³⁰ Public Health Scotland, Edinburgh, UK.
³¹ Usher Institute, University of Edinburgh, Edinburgh, UK.
³² Department of Maternity and Sexual Health Team, Public Health Scotland, Edinburgh, UK.
³³ Catholic University of the Maule, Región del Maule, Chile.
³⁴ Department of Wellness and Health, Catholic University of Uruguay, Montevideo, Uruguay.

PMID: 37156241
DOI: 10.1111/1471-0528.17505

Abstract

Objective: To examine the prevalence of novel newborn types among 165 million live births in 23 countries from 2000 to 2021.

Design: Population-based, multi-country analysis.

Setting: National data systems in 23 middle- and high-income countries.

Population: Liveborn infants.

Methods: Country teams with high-quality data were invited to be part of the Vulnerable Newborn Measurement Collaboration. We classified live births by six newborn types based on gestational age information (preterm <37 weeks versus term ≥37 weeks) and size for gestational age defined as small (SGA, <10th centile), appropriate (10th-90th centiles), or large (LGA, >90th centile) for gestational age, according to INTERGROWTH-21st standards. We considered small newborn types of any combination of preterm or SGA, and term + LGA was considered large. Time trends were analysed using 3-year moving averages for small and large types.

Main outcome measures: Prevalence of six newborn types.

Results: We analysed 165 017 419 live births and the median prevalence of small types was 11.7% - highest in Malaysia (26%) and Qatar (15.7%). Overall, 18.1% of newborns were large (term + LGA) and was highest in Estonia 28.8% and Denmark 25.9%. Time trends of small and large infants were relatively stable in most countries.

Conclusions: The distribution of newborn types varies across the 23 middle- and high-income countries. Small newborn types were highest in west Asian countries and large types were highest in Europe. To better understand the global patterns of these novel newborn types, more information is needed, especially from low- and middle-income countries.

Keywords: low birthweight; newborn; preterm birth; size for gestational age.

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References

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Vulnerable newborn types: Analysis of population-based registries for 165 million births in 23 countries, 2000-2021

Collaborators

Affiliations

Vulnerable newborn types: Analysis of population-based registries for 165 million births in 23 countries, 2000-2021

Authors

Collaborators

Affiliations

Abstract

References

REFERENCES

LinkOut - more resources

Full Text Sources