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. 2023 May 8;13(5):e068076.
doi: 10.1136/bmjopen-2022-068076.

Serum folate deficiency and associated factors among pregnant women in Haramaya District, Eastern Ethiopia: a community-based study

Newas Yusuf Mamme  1 , Hirbo Shore Roba  1 , Meseret Belete Fite  2 , Gemechu Asefa  1 , Jemal Abrahim  1 , Mohammed Yuya  1 , Tara Wilfong  1 , Demiraw Bikila Gurmu  3 , Feyissa Challa Waka  3 , Masresha Tessema  4 , Wossene Habtu  3 , Meseret Woldeyohannes  4 , Temam Beshir Raru  1 , Mohammed Abdurke Kure  5 , Dawit Alemayehu  4 , Aboma Motuma  5 , Kedir Teji Roba  6
Affiliations

Serum folate deficiency and associated factors among pregnant women in Haramaya District, Eastern Ethiopia: a community-based study

Newas Yusuf Mamme et al. BMJ Open. .

Abstract

Objectives: We aimed to estimate the prevalence of folate deficiency and contributing factors among pregnant women.

Design: A community-based, cross-sectional study.

Setting: Haramaya District, Eastern Ethiopia.

Participants: Four hundred and forty-six pregnant women participated in the study.

Primary outcome measure: The prevalence of folate deficiency and risk factors.

Results: Overall, the prevalence of folate deficiency was 49.3% (95% CI 44.6% to 54.1%). Pregnant women with iron deficiency anaemia were 2.94 times more likely to develop folate deficiency (adjusted OR (AOR)=2.9, 95% CI 1.9 to 4.7). Respondents with good knowledge of folate-rich foods (AOR=0.3, 95% CI 0.1 to 0.7) and those who took iron and folic acid supplementation (AOR=0.6, 95% CI 0.4 to 0.9) during their pregnancy were less likely to develop folate deficiency.

Conclusions: In this study, a considerable proportion of pregnant women had folate deficiency during their pregnancy. Therefore, it is critical that nutritional treatment, education and counselling be strengthened to facilitate iron and folic acid supplementation during pregnancy.

Keywords: Anaemia; NUTRITION & DIETETICS; Nutritional support; PUBLIC HEALTH; Public health.

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Conflict of interest statement

Competing interests: None declared.

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